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XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies.
Patel E, Malkova NV, Crowe D, Pederzoli-Ribeil M, Fantini D, Fanny M, Madala HR, Jenkins KA, Yerov O, Greene J, Guzman W, O'Toole C, Taylor J, O'Donnell RK, Johnson P, Lanter BB, Ames B, Chen J, Vu S, Wu HJ, Cantin S, McLaughlin M, Hsiao YS, Tomar DS, Rozenfeld R, Thiruneelakantapillai L, O'Hagan RC, Nicholson B, O'Neil J, Bialucha CU. Patel E, et al. Mol Cancer Ther. 2024 Apr 2;23(4):421-435. doi: 10.1158/1535-7163.MCT-23-0336. Mol Cancer Ther. 2024. PMID: 38030380 Free PMC article.
XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer.
Jenkins KA, Park M, Pederzoli-Ribeil M, Eskiocak U, Johnson P, Guzman W, McLaughlin M, Moore-Lai D, O'Toole C, Liu Z, Nicholson B, Flesch V, Qiu H, Clackson T, O'Hagan RC, Rodeck U, Karow M, O'Neil J, Williams JC. Jenkins KA, et al. Among authors: o toole c. J Immunother Cancer. 2023 Dec 12;11(12):e007785. doi: 10.1136/jitc-2023-007785. J Immunother Cancer. 2023. PMID: 38164757 Free PMC article.
Longitudinal serum bicarbonate and mortality risk in older patients with advanced chronic kidney disease: analyses from the EQUAL cohort.
Lombardi G, Chesnaye NC, Caskey FJ, Dekker FW, Evans M, Heimburger O, Pippias M, Torino C, Szymczak M, Drechsler C, Wanner C, Gambaro G, Stel VS, Jager KJ, Ferraro PM; EQUAL study investigators. Lombardi G, et al. Clin Kidney J. 2024 Aug 22;17(11):sfae254. doi: 10.1093/ckj/sfae254. eCollection 2024 Nov. Clin Kidney J. 2024. PMID: 39669396 Free PMC article.
Association between Chronic Kidney Disease-Mineral and Bone Disorder Biomarkers and Symptom Burden in Older Patients with Advanced Chronic Kidney Disease: Results from the EQUAL Study.
Magagnoli L, Cozzolino M, Evans M, Caskey FJ, Dekker FW, Torino C, Szymczak M, Drechsler C, Pippias M, Vilasi A, Janse RJ, Krajewska M, Stel VS, Jager KJ, Chesnaye NC; EQUAL study investigators. Magagnoli L, et al. Clin J Am Soc Nephrol. 2024 Oct 1;19(10):1240-1252. doi: 10.2215/CJN.0000000000000510. Epub 2024 Jul 22. Clin J Am Soc Nephrol. 2024. PMID: 39037951
2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons.
Shi J, Nutkovich B, Kushinsky D, Rao BY, Herrlinger SA, Tsivourakis E, Mihaila TS, Paredes MEC, Malina KC, O'Toole CK, Yong HC, Sanner BM, Xie A, Varol E, Losonczy A, Spiegel I. Shi J, et al. Among authors: o toole ck. bioRxiv [Preprint]. 2024 Sep 4:2024.03.21.586118. doi: 10.1101/2024.03.21.586118. bioRxiv. 2024. PMID: 38585980 Free PMC article. Preprint.
159 results