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Divergent molecular networks program functionally distinct CD8+ skin-resident memory T cells.
Park SL, Christo SN, Wells AC, Gandolfo LC, Zaid A, Alexandre YO, Burn TN, Schröder J, Collins N, Han SJ, Guillaume SM, Evrard M, Castellucci C, Davies B, Osman M, Obers A, McDonald KM, Wang H, Mueller SN, Kannourakis G, Berzins SP, Mielke LA, Carbone FR, Kallies A, Speed TP, Belkaid Y, Mackay LK. Park SL, et al. Among authors: mielke la. Science. 2023 Dec;382(6674):1073-1079. doi: 10.1126/science.adi8885. Epub 2023 Nov 30. Science. 2023. PMID: 38033053
The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.
Vasanthakumar A, Moro K, Xin A, Liao Y, Gloury R, Kawamoto S, Fagarasan S, Mielke LA, Afshar-Sterle S, Masters SL, Nakae S, Saito H, Wentworth JM, Li P, Liao W, Leonard WJ, Smyth GK, Shi W, Nutt SL, Koyasu S, Kallies A. Vasanthakumar A, et al. Among authors: mielke la. Nat Immunol. 2015 Mar;16(3):276-85. doi: 10.1038/ni.3085. Epub 2015 Jan 19. Nat Immunol. 2015. PMID: 25599561
TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis.
Mielke LA, Liao Y, Clemens EB, Firth MA, Duckworth B, Huang Q, Almeida FF, Chopin M, Koay HF, Bell CA, Hediyeh-Zadeh S, Park SL, Raghu D, Choi J, Putoczki TL, Hodgkin PD, Franks AE, Mackay LK, Godfrey DI, Davis MJ, Xue HH, Bryant VL, Kedzierska K, Shi W, Belz GT. Mielke LA, et al. J Exp Med. 2019 Jul 1;216(7):1682-1699. doi: 10.1084/jem.20181778. Epub 2019 May 29. J Exp Med. 2019. PMID: 31142588 Free PMC article.
The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues.
Vasanthakumar A, Liao Y, Teh P, Pascutti MF, Oja AE, Garnham AL, Gloury R, Tempany JC, Sidwell T, Cuadrado E, Tuijnenburg P, Kuijpers TW, Lalaoui N, Mielke LA, Bryant VL, Hodgkin PD, Silke J, Smyth GK, Nolte MA, Shi W, Kallies A. Vasanthakumar A, et al. Among authors: mielke la. Cell Rep. 2017 Sep 19;20(12):2906-2920. doi: 10.1016/j.celrep.2017.08.068. Epub 2017 Sep 7. Cell Rep. 2017. PMID: 28889989 Free article.
53 results