Shmulevitz M - Search Results

1

Improved oncolytic activity of a reovirus mutant that displays enhanced virus spread due to reduced cell attachment.

Cristi F, Walters M, Narayan N, Agopsowicz K, Hitt MM, Shmulevitz M. Cristi F, et al. Among authors: shmulevitz m. Mol Ther Oncolytics. 2023 Nov 2;31:100743. doi: 10.1016/j.omto.2023.100743. eCollection 2023 Dec 19. Mol Ther Oncolytics. 2023. PMID: 38033400 Free PMC article.

2

Novel High-throughput Approach for Purification of Infectious Virions.

James KT, Cooney B, Agopsowicz K, Trevors MA, Mohamed A, Stoltz D, Hitt M, Shmulevitz M. James KT, et al. Among authors: shmulevitz m. Sci Rep. 2016 Nov 9;6:36826. doi: 10.1038/srep36826. Sci Rep. 2016. PMID: 27827454 Free PMC article.

3

Breast Tumor-Associated Metalloproteases Restrict Reovirus Oncolysis by Cleaving the σ1 Cell Attachment Protein and Can Be Overcome by Mutation of σ1.

Fernandes JP, Cristi F, Eaton HE, Chen P, Haeflinger S, Bernard I, Hitt MM, Shmulevitz M. Fernandes JP, et al. Among authors: shmulevitz m. J Virol. 2019 Oct 29;93(22):e01380-19. doi: 10.1128/JVI.01380-19. Print 2019 Nov 15. J Virol. 2019. PMID: 31462562 Free PMC article.

4

Polymorphisms in the Most Oncolytic Reovirus Strain Confer Enhanced Cell Attachment, Transcription, and Single-Step Replication Kinetics.

Mohamed A, Smiley JR, Shmulevitz M. Mohamed A, et al. Among authors: shmulevitz m. J Virol. 2020 Jan 31;94(4):e01937-19. doi: 10.1128/JVI.01937-19. Print 2020 Jan 31. J Virol. 2020. PMID: 31776267 Free PMC article.

5

The reovirus μ2 C-terminal loop inversely regulates NTPase and transcription functions versus binding to factory-forming μNS and promotes replication in tumorigenic cells.

Yip WKW, Cristi F, Trifonov G, Narayan N, Kubanski M, Shmulevitz M. Yip WKW, et al. Among authors: shmulevitz m. J Virol. 2021 Apr 26;95(10):e02006-20. doi: 10.1128/JVI.02006-20. Epub 2021 Mar 3. J Virol. 2021. PMID: 33658345 Free PMC article.

6

Genetic Modifications That Expand Oncolytic Virus Potency.

Cristi F, Gutiérrez T, Hitt MM, Shmulevitz M. Cristi F, et al. Among authors: shmulevitz m. Front Mol Biosci. 2022 Jan 26;9:831091. doi: 10.3389/fmolb.2022.831091. eCollection 2022. Front Mol Biosci. 2022. PMID: 35155581 Free PMC article. Review.

7

Exploring host factors that impact reovirus replication, dissemination, and reovirus-induced cell death in cancer versus normal cells in culture.

Shmulevitz M, Lee PW. Shmulevitz M, et al. Methods Mol Biol. 2012;797:163-76. doi: 10.1007/978-1-61779-340-0_12. Methods Mol Biol. 2012. PMID: 21948476

8

Reduction of virion-associated σ1 fibers on oncolytic reovirus variants promotes adaptation toward tumorigenic cells.

Mohamed A, Teicher C, Haefliger S, Shmulevitz M. Mohamed A, et al. Among authors: shmulevitz m. J Virol. 2015 Apr;89(8):4319-34. doi: 10.1128/JVI.03651-14. Epub 2015 Feb 4. J Virol. 2015. PMID: 25653434 Free PMC article.

9

Oncolytic activity of reovirus in HPV positive and negative head and neck squamous cell carcinoma.

Cooper T, Biron VL, Fast D, Tam R, Carey T, Shmulevitz M, Seikaly H. Cooper T, et al. Among authors: shmulevitz m. J Otolaryngol Head Neck Surg. 2015 Feb 24;44(1):8. doi: 10.1186/s40463-015-0062-x. J Otolaryngol Head Neck Surg. 2015. PMID: 25890191 Free PMC article.

10

Oncolytic reovirus induces intracellular redistribution of Ras to promote apoptosis and progeny virus release.

Garant KA, Shmulevitz M, Pan L, Daigle RM, Ahn DG, Gujar SA, Lee PW. Garant KA, et al. Among authors: shmulevitz m. Oncogene. 2016 Feb 11;35(6):771-82. doi: 10.1038/onc.2015.136. Epub 2015 May 11. Oncogene. 2016. PMID: 25961930

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