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Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma.
Liu Y, Zhan Z, Kang Z, Li M, Lv Y, Li S, Tong L, Feng F, Li Y, Zhang M, Xue Y, Chen Y, Zhang T, Song P, Su Y, Shen Y, Sun Y, Yang X, Chen Y, Yao S, Yang H, Wang C, Geng M, Li W, Duan W, Xie H, Ding J. Liu Y, et al. Among authors: zhan z. Acta Pharm Sin B. 2023 Dec;13(12):4748-4764. doi: 10.1016/j.apsb.2023.09.009. Epub 2023 Sep 22. Acta Pharm Sin B. 2023. PMID: 38045044 Free PMC article.
O-linked triazolotriazines: potent and selective c-Met inhibitors.
Chen F, Wang Y, Ai J, Zhan Z, Lv Y, Liang Z, Luo C, Mei D, Geng M, Duan W. Chen F, et al. Among authors: zhan z. ChemMedChem. 2012 Jul;7(7):1276-85. doi: 10.1002/cmdc.201200145. Epub 2012 Apr 26. ChemMedChem. 2012. PMID: 22539497
Synthesis of triazolotriazine derivatives as c-Met inhibitors.
Guo Y, Peng X, Ji Y, Zhang Y, Ding J, Zhan Z, Ai J, Duan W. Guo Y, et al. Among authors: zhan z. Mol Divers. 2021 May;25(2):839-846. doi: 10.1007/s11030-020-10067-5. Epub 2020 Mar 10. Mol Divers. 2021. PMID: 32157572
1,818 results