Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

26,565 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Moroccan natural products for multitarget-based treatment of Alzheimer's disease: A computational study.
Guerguer FZ, Bouribab A, Karim EM, Khedraoui M, Amegrissi F, Raouf YS, Samadi A, Chtita S. Guerguer FZ, et al. PLoS One. 2025 Jan 16;20(1):e0313411. doi: 10.1371/journal.pone.0313411. eCollection 2025. PLoS One. 2025. PMID: 39820594
Acetylcholinesterase, Butyrylcholinesterase, Monoamine Oxidase B, Beta-Secretase, and Glycogen Synthase Kinase Beta play central roles in its pathogenesis. ...
Acetylcholinesterase, Butyrylcholinesterase, Monoamine Oxidase B, Beta-Secretase, and Glycogen Synthase Kinase Beta play centr …
Taurine protection attenuates bisphenol-A-induced behavioral, neurochemical, and histopathological alterations in male rats.
Nazmy MM, Noor NA, Mohammed FF, Khadrawy YA, Radwan NM. Nazmy MM, et al. Naunyn Schmiedebergs Arch Pharmacol. 2025 Jan 17. doi: 10.1007/s00210-024-03767-4. Online ahead of print. Naunyn Schmiedebergs Arch Pharmacol. 2025. PMID: 39820545
An open-field test was used to measure motor activity. The changes in monoamines, monoamine oxidase (MAO), acetylcholinesterase (AChE), Na(+),K(+),ATPase, oxidative stress, caspase-3, and histopathology were evaluated in the cortical and hippocampal tissues of all g …
An open-field test was used to measure motor activity. The changes in monoamines, monoamine oxidase (MAO), acetylcholinesteras …
JARID1D-dependent androgen receptor and JunD signaling activation of osteoclast differentiation inhibits prostate cancer bone metastasis through demethylating H3K4.
Hu Y, Zhao Z, Xie Q, Li H, Zhang C, He X, Ma Y, Zhang C, Li Q, Shi C. Hu Y, et al. Theranostics. 2025 Jan 1;15(4):1320-1337. doi: 10.7150/thno.104135. eCollection 2025. Theranostics. 2025. PMID: 39816691 Free PMC article.
Further analysis using western blotting and bone culture systems indicated that knocking down JARID1D enhanced the expression of monoamine oxidase A (MAOA) through the AR signaling pathway, leading to increased secretion of the nuclear factor kappa B (NF-kappaB) lig …
Further analysis using western blotting and bone culture systems indicated that knocking down JARID1D enhanced the expression of monoamin …
SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer's disease.
Bhalla M, Joo J, Kim D, Shin JI, Park YM, Ju YH, Park U, Yoo S, Hyeon SJ, Lee H, Lee J, Ryu H, Lee CJ. Bhalla M, et al. Mol Neurodegener. 2025 Jan 15;20(1):6. doi: 10.1186/s13024-024-00788-8. Mol Neurodegener. 2025. PMID: 39815261 Free PMC article.
Astrocytic GABA and H(2)O(2) are associated with memory impairment in AD and synthesized through the Monoamine Oxidase B (MAOB)-mediated multi-step degradation of putrescine. However, the enzymes downstream to MAOB in this pathway remain unidentified. ...
Astrocytic GABA and H(2)O(2) are associated with memory impairment in AD and synthesized through the Monoamine Oxidase B (MAOB …
Aryl Hydrocarbon Receptor Establishes a Delicate Balance between the Level of the Trace Amine Tryptamine and Monoamine Oxidase Activity in the Brain and Periphery in Health and Conditions such as Neurodegenerative, Neurodevelopmental, and Psychiatric Disorders.
Kot M. Kot M. Curr Neuropharmacol. 2025 Jan 13. doi: 10.2174/011570159X340635241022113450. Online ahead of print. Curr Neuropharmacol. 2025. PMID: 39812050
The purpose of this review was to analyse the literature regarding the correlation between the level of tryptamine, aryl hydrocarbon receptor (AHR) signalling pathway activation, and monoamine oxidase (MAO)-A and MAO-B activity in health and conditions …
The purpose of this review was to analyse the literature regarding the correlation between the level of tryptamine, aryl hydrocarbon recepto …
Optimizing Linezolid: Transforming It into a Selective MAO-B Inhibitor via a Toxicity-to-Activity Optimization Approach.
Dhangar MS, Ahmad I, Oh JM, Patil BR, Chinnam S, Sriram D, Kumari J, Mathew B, Sayyed RA, Chaudhari SB, Ansari SA, Rai N, Kim H, Patel HM. Dhangar MS, et al. ACS Med Chem Lett. 2024 Dec 16;16(1):40-50. doi: 10.1021/acsmedchemlett.4c00354. eCollection 2025 Jan 9. ACS Med Chem Lett. 2024. PMID: 39811132
Linezolid, a widely used oxazolidinone antibiotic, exhibits potent activity against resistant bacterial infections but is associated with serotonergic toxicity, primarily due to its inhibition of monoamine oxidase (MAO). MAOs, consisting of MAO-A and M …
Linezolid, a widely used oxazolidinone antibiotic, exhibits potent activity against resistant bacterial infections but is associated with se …
Multi-target-directed therapeutic strategies for Alzheimer's disease: controlling amyloid-β aggregation, metal ion homeostasis, and enzyme inhibition.
Yoo J, Lee J, Ahn B, Han J, Lim MH. Yoo J, et al. Chem Sci. 2025 Jan 6. doi: 10.1039/d4sc06762b. Online ahead of print. Chem Sci. 2025. PMID: 39810997 Free PMC article. Review.
This review illustrates their interrelationships, with a particular emphasis on the interplay among Abeta, metal ions, and AD-related enzymes, such as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1), matrix metalloproteinase 9 (MMP9), lysyl oxidase-like 2 (LO …
This review illustrates their interrelationships, with a particular emphasis on the interplay among Abeta, metal ions, and AD-related enzyme …
Conformation Study and Design of Novel 6-Hydroxybenzothiazole-2-Carboxamides as Potentially Potent and Selective Monoamine Oxidase B Inhibitors for Neuroprotection.
Xie D, Guo P, Zhao Q, Gao Y, Zhang J, Zhou J. Xie D, et al. Curr Top Med Chem. 2025 Jan 10. doi: 10.2174/0115680266354743241216065502. Online ahead of print. Curr Top Med Chem. 2025. PMID: 39810525
BACKGROUND: 6-hydroxybenzothiazole-2-carboxamide is a novel, potent, and specific monoamine oxidase B inhibitor that can be used to study the structure of molecules and come up with new ways to protect neurons. OBJECTIVE: The objective of this work was to create an …
BACKGROUND: 6-hydroxybenzothiazole-2-carboxamide is a novel, potent, and specific monoamine oxidase B inhibitor that can be us …
26,565 results
You have reached the last available page of results. Please see the User Guide for more information.