Wang L - Search Results

1

A proteome-wide screen identifies the calcium binding proteins, S100A8/S100A9, as clinically relevant therapeutic targets in aortic dissection.

Jiang H, Zhao Y, Su M, Sun L, Chen M, Zhang Z, Ilyas I, Wang Z, Little PJ, Wang L, Weng J, Ge J, Xu S. Jiang H, et al. Among authors: wang l, wang z. Pharmacol Res. 2024 Jan;199:107029. doi: 10.1016/j.phrs.2023.107029. Epub 2023 Dec 5. Pharmacol Res. 2024. PMID: 38056513 Free article.

2

AMPK-Dependent YAP Inhibition Mediates the Protective Effect of Metformin against Obesity-Associated Endothelial Dysfunction and Inflammation.

Kang L, Yi J, Lau CW, He L, Chen Q, Xu S, Li J, Xia Y, Zhang Y, Huang Y, Wang L. Kang L, et al. Among authors: wang l. Antioxidants (Basel). 2023 Aug 28;12(9):1681. doi: 10.3390/antiox12091681. Antioxidants (Basel). 2023. PMID: 37759984 Free PMC article.

3

Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E-deficient mice.

Xu MY, Xu JJ, Kang LJ, Liu ZH, Su MM, Zhao WQ, Wang ZH, Sun L, Xiao JB, Evans PC, Tian XY, Wang L, Huang Y, Liang XM, Weng JP, Xu SW. Xu MY, et al. Among authors: wang zh, wang l. Acta Pharmacol Sin. 2024 Nov;45(11):2277-2289. doi: 10.1038/s41401-024-01317-5. Epub 2024 Jun 17. Acta Pharmacol Sin. 2024. PMID: 38886550

4

SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysis.

Cheng CK, Lin X, Pu Y, Tse JKY, Wang Y, Zhang CL, Cao X, Lau CW, Huang J, He L, Luo JY, Shih YT, Wan S, Ng CF, Wang L, Ma RCW, Chiu JJ, Chan TF, Yu Tian X, Huang Y. Cheng CK, et al. Among authors: wang l, wang y. J Adv Res. 2023 Jan;43:187-203. doi: 10.1016/j.jare.2022.02.017. Epub 2022 Mar 1. J Adv Res. 2023. PMID: 36585108 Free PMC article.

5

Molecular mechanisms and therapeutic perspectives of peroxisome proliferator-activated receptor α agonists in cardiovascular health and disease.

Pu Y, Cheng CK, Zhang H, Luo JY, Wang L, Tomlinson B, Huang Y. Pu Y, et al. Among authors: wang l. Med Res Rev. 2023 Nov;43(6):2086-2114. doi: 10.1002/med.21970. Epub 2023 Apr 29. Med Res Rev. 2023. PMID: 37119045 Review.

6

Curaxin CBL0137 inhibits endothelial inflammation and atherogenesis via suppression of the Src-YAP signalling axis.

Ding H, Jiang M, Lau CW, Luo J, Chan AM, Wang L, Huang Y. Ding H, et al. Among authors: wang l. Br J Pharmacol. 2023 Apr;180(8):1168-1185. doi: 10.1111/bph.16007. Epub 2022 Dec 29. Br J Pharmacol. 2023. PMID: 36495259 Free article.

7

Thioridazine protects against disturbed flow-induced atherosclerosis by inhibiting RhoA/YAP-mediated endothelial inflammation.

Jiang MC, Ding HY, Huang YH, Cheng CK, Lau CW, Xia Y, Yao XQ, Wang L, Huang Y. Jiang MC, et al. Among authors: wang l. Acta Pharmacol Sin. 2023 Oct;44(10):1977-1988. doi: 10.1038/s41401-023-01102-w. Epub 2023 May 22. Acta Pharmacol Sin. 2023. PMID: 37217602 Free PMC article.

8

Targeting the tyrosine kinase Src in endothelium attenuates inflammation and atherogenesis induced by disturbed flow.

Ding H, Jiang M, Chan AM, Xia Y, Ma RCW, Yao X, Wang L, Huang Y. Ding H, et al. Among authors: wang l. Br J Pharmacol. 2024 Aug 8. doi: 10.1111/bph.17307. Online ahead of print. Br J Pharmacol. 2024. PMID: 39117589

9

Aged Gut Microbiome Induces Metabolic Impairment and Hallmarks of Vascular and Intestinal Aging in Young Mice.

Cheng CK, Ye L, Zuo Y, Wang Y, Wang L, Li F, Chen S, Huang Y. Cheng CK, et al. Among authors: wang l, wang y. Antioxidants (Basel). 2024 Oct 17;13(10):1250. doi: 10.3390/antiox13101250. Antioxidants (Basel). 2024. PMID: 39456503 Free PMC article.

10

The role of KLF2 in regulating hepatic lipogenesis and blood cholesterol homeostasis via the SCAP/SREBP pathway.

Huang Y, Wang YF, Ruan XZ, Lau CW, Wang L, Huang Y. Huang Y, et al. Among authors: wang yf, wang l. J Lipid Res. 2024 Jan;65(1):100472. doi: 10.1016/j.jlr.2023.100472. Epub 2023 Nov 9. J Lipid Res. 2024. PMID: 37949368 Free PMC article.

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