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GABA(A) receptor activation drives GABARAP-Nix mediated autophagy to radiation-sensitize primary and brain-metastatic lung adenocarcinoma tumors.
Bhattacharya D, Barille R, Toukam DK, Gawali VS, Kallay L, Ahmed T, Brown H, Rezvanian S, Karve A, Desai PB, Medvedovic M, Wang K, Ionascu D, Harun N, Wang C, Baschnagel AM, Kritzer JA, Cook JM, Pomeranz Krummel DA, Sengupta S. Bhattacharya D, et al. Among authors: sengupta s. bioRxiv [Preprint]. 2023 Dec 1:2023.11.29.569295. doi: 10.1101/2023.11.29.569295. bioRxiv. 2023. Update in: Cancers (Basel). 2024 Sep 15;16(18):3167. doi: 10.3390/cancers16183167 PMID: 38076805 Free PMC article. Updated. Preprint.
Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death.
Kallay L, Keskin H, Ross A, Rupji M, Moody OA, Wang X, Li G, Ahmed T, Rashid F, Stephen MR, Cottrill KA, Nuckols TA, Xu M, Martinson DE, Tranghese F, Pei Y, Cook JM, Kowalski J, Taylor MD, Jenkins A, Pomeranz Krummel DA, Sengupta S. Kallay L, et al. Among authors: sengupta s. J Neurooncol. 2019 May;142(3):411-422. doi: 10.1007/s11060-019-03115-0. Epub 2019 Feb 6. J Neurooncol. 2019. PMID: 30725256 Free PMC article.
Impact of Sequencing Radiation Therapy and Immune Checkpoint Inhibitors in the Treatment of Melanoma Brain Metastases.
Pomeranz Krummel DA, Nasti TH, Izar B, Press RH, Xu M, Lowder L, Kallay L, Rupji M, Rosen H, Su J, Curran W, Olson J, Weinberg B, Schniederjan M, Neill S, Lawson D, Kowalski J, Khan MK, Sengupta S. Pomeranz Krummel DA, et al. Among authors: sengupta s. Int J Radiat Oncol Biol Phys. 2020 Sep 1;108(1):157-163. doi: 10.1016/j.ijrobp.2020.01.043. Epub 2020 Feb 11. Int J Radiat Oncol Biol Phys. 2020. PMID: 32057994 Free PMC article.
Epigenetics and survivorship in pediatric brain tumor patients.
Bhattacharya D, Pomeroy SL, Pomeranz Krummel DA, Sengupta S. Bhattacharya D, et al. Among authors: sengupta s. J Neurooncol. 2020 Oct;150(1):77-83. doi: 10.1007/s11060-020-03535-3. Epub 2020 May 25. J Neurooncol. 2020. PMID: 32451770 Review.
Melanoma Cell Intrinsic GABAA Receptor Enhancement Potentiates Radiation and Immune Checkpoint Inhibitor Response by Promoting Direct and T Cell-Mediated Antitumor Activity.
Pomeranz Krummel DA, Nasti TH, Kaluzova M, Kallay L, Bhattacharya D, Melms JC, Izar B, Xu M, Burnham A, Ahmed T, Li G, Lawson D, Kowalski J, Cao Y, Switchenko JM, Ionascu D, Cook JM, Medvedovic M, Jenkins A, Khan MK, Sengupta S. Pomeranz Krummel DA, et al. Among authors: sengupta s. Int J Radiat Oncol Biol Phys. 2021 Mar 15;109(4):1040-1053. doi: 10.1016/j.ijrobp.2020.10.025. Epub 2020 Oct 24. Int J Radiat Oncol Biol Phys. 2021. PMID: 33289666 Free PMC article.
Reuse of Molecules for Glioblastoma Therapy.
Koehler A, Karve A, Desai P, Arbiser J, Plas DR, Qi X, Read RD, Sasaki AT, Gawali VS, Toukam DK, Bhattacharya D, Kallay L, Pomeranz Krummel DA, Sengupta S. Koehler A, et al. Among authors: sengupta s. Pharmaceuticals (Basel). 2021 Jan 28;14(2):99. doi: 10.3390/ph14020099. Pharmaceuticals (Basel). 2021. PMID: 33525329 Free PMC article. Review.
Therapeutically leveraging GABAA receptors in cancer.
Bhattacharya D, Gawali VS, Kallay L, Toukam DK, Koehler A, Stambrook P, Krummel DP, Sengupta S. Bhattacharya D, et al. Among authors: sengupta s. Exp Biol Med (Maywood). 2021 Oct;246(19):2128-2135. doi: 10.1177/15353702211032549. Exp Biol Med (Maywood). 2021. PMID: 34649481 Free PMC article. Review.
Ligand-Gated Ion Channels as Targets for Treatment and Management of Cancers.
Rao R, Shah S, Bhattacharya D, Toukam DK, Cáceres R, Pomeranz Krummel DA, Sengupta S. Rao R, et al. Among authors: sengupta s. Front Physiol. 2022 Mar 8;13:839437. doi: 10.3389/fphys.2022.839437. eCollection 2022. Front Physiol. 2022. PMID: 35350689 Free PMC article. Review.
2,999 results