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Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival.
Tzouanas CN, Sherman MS, Shay JES, Rubin AJ, Mead BE, Dao TT, Butzlaff T, Mana MD, Kolb KE, Walesky C, Pepe-Mooney BJ, Smith CJ, Prakadan SM, Ramseier ML, Tong EY, Joung J, Chi F, McMahon-Skates T, Winston CL, Jeong WJ, Aney KJ, Chen E, Nissim S, Zhang F, Deshpande V, Lauer GM, Yilmaz ÖH, Goessling W, Shalek AK. Tzouanas CN, et al. Among authors: walesky c. bioRxiv [Preprint]. 2023 Dec 1:2023.11.30.569407. doi: 10.1101/2023.11.30.569407. bioRxiv. 2023. PMID: 38077056 Free PMC article. Preprint.
Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis.
McGreal SR, Bhushan B, Walesky C, McGill MR, Lebofsky M, Kandel SE, Winefield RD, Jaeschke H, Zachara NE, Zhang Z, Tan EP, Slawson C, Apte U. McGreal SR, et al. Among authors: walesky c. Toxicol Sci. 2018 Apr 1;162(2):599-610. doi: 10.1093/toxsci/kfy002. Toxicol Sci. 2018. PMID: 29325178 Free PMC article.
WNTing no RASt for hepatocellular carcinoma.
Walesky C, Goessling W. Walesky C, et al. Hepatology. 2017 May;65(5):1435-1437. doi: 10.1002/hep.29157. Epub 2017 Mar 31. Hepatology. 2017. PMID: 28295459 No abstract available.
Advances in cholangiocarcinoma research: report from the third Cholangiocarcinoma Foundation Annual Conference.
Abou-Alfa GK, Andersen JB, Chapman W, Choti M, Forbes SJ, Gores GJ, Hong TS, Harding JJ, Vander Heiden MG, Javle M, Kelley RK, Kwong LN, Lowery M, Merrell A, Miyabe K, Rhim A, Saha S, Sia D, Tanasanvimon S, Venook A, Valle JW, Walesky C, Whetstine J, Willenbring H, Zhu AX, Mayer D, Stanger BZ. Abou-Alfa GK, et al. Among authors: walesky c. J Gastrointest Oncol. 2016 Dec;7(6):819-827. doi: 10.21037/jgo.2016.11.11. J Gastrointest Oncol. 2016. PMID: 28078106 Free PMC article. No abstract available.
Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling.
Sun L, Beggs K, Borude P, Edwards G, Bhushan B, Walesky C, Roy N, Manley MW Jr, Gunewardena S, O'Neil M, Li H, Apte U. Sun L, et al. Among authors: walesky c. Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1;311(1):G91-G104. doi: 10.1152/ajpgi.00027.2015. Epub 2016 May 5. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27151938 Free PMC article.
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