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Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.
Nomura M, Ohuchi M, Sakamoto Y, Kudo K, Yaku K, Soga T, Sugiura Y, Morita M, Hayashi K, Miyahara S, Sato T, Yamashita Y, Ito S, Kikuchi N, Sato I, Saito R, Yaegashi N, Fukuhara T, Yamada H, Shima H, Nakayama KI, Hirao A, Kawasaki K, Arai Y, Akamatsu S, Tanuma SI, Sato T, Nakagawa T, Tanuma N. Nomura M, et al. Among authors: tanuma n. Nat Commun. 2023 Dec 13;14(1):8095. doi: 10.1038/s41467-023-43630-3. Nat Commun. 2023. PMID: 38092728 Free PMC article.
pp32/ I-1(PP2A) negatively regulates the Raf-1/MEK/ERK pathway.
Fukukawa C, Tanuma N, Okada T, Kikuchi K, Shima H. Fukukawa C, et al. Among authors: tanuma n. Cancer Lett. 2005 Aug 26;226(2):155-60. doi: 10.1016/j.canlet.2004.11.026. Epub 2004 Dec 16. Cancer Lett. 2005. PMID: 16039954
Nuclear inhibitor of protein phosphatase-1 (NIPP1) directs protein phosphatase-1 (PP1) to dephosphorylate the U2 small nuclear ribonucleoprotein particle (snRNP) component, spliceosome-associated protein 155 (Sap155).
Tanuma N, Kim SE, Beullens M, Tsubaki Y, Mitsuhashi S, Nomura M, Kawamura T, Isono K, Koseki H, Sato M, Bollen M, Kikuchi K, Shima H. Tanuma N, et al. J Biol Chem. 2008 Dec 19;283(51):35805-14. doi: 10.1074/jbc.M805468200. Epub 2008 Oct 8. J Biol Chem. 2008. PMID: 18842582 Free article.
127 results