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Page 1
Human iPSC-derived microglia carrying the LRRK2-G2019S mutation show a Parkinson's disease related transcriptional profile and function.
Ohtonen S, Giudice L, Jäntti H, Fazaludeen MF, Shakirzyanova A, Gómez-Budia M, Välimäki NN, Niskanen J, Korvenlaita N, Fagerlund I, Koistinaho J, Amiry-Moghaddam M, Savchenko E, Roybon L, Lehtonen Š, Korhonen P, Malm T. Ohtonen S, et al. Among authors: valimaki nn. Sci Rep. 2023 Dec 13;13(1):22118. doi: 10.1038/s41598-023-49294-9. Sci Rep. 2023. PMID: 38092815 Free PMC article.
Early Alzheimer's disease pathology in human cortex involves transient cell states.
Gazestani V, Kamath T, Nadaf NM, Dougalis A, Burris SJ, Rooney B, Junkkari A, Vanderburg C, Pelkonen A, Gomez-Budia M, Välimäki NN, Rauramaa T, Therrien M, Koivisto AM, Tegtmeyer M, Herukka SK, Abdulraouf A, Marsh SE, Hiltunen M, Nehme R, Malm T, Stevens B, Leinonen V, Macosko EZ. Gazestani V, et al. Among authors: valimaki nn. Cell. 2023 Sep 28;186(20):4438-4453.e23. doi: 10.1016/j.cell.2023.08.005. Cell. 2023. PMID: 37774681 Free PMC article.
Alzheimer's disease-induced phagocytic microglia express a specific profile of coding and non-coding RNAs.
Scoyni F, Giudice L, Väänänen MA, Downes N, Korhonen P, Choo XY, Välimäki NN, Mäkinen P, Korvenlaita N, Rozemuller AJ, de Vries HE, Polo J, Turunen TA, Ylä-Herttuala S, Hansen TB, Grubman A, Kaikkonen MU, Malm T. Scoyni F, et al. Among authors: valimaki nn. Alzheimers Dement. 2024 Feb;20(2):954-974. doi: 10.1002/alz.13502. Epub 2023 Oct 12. Alzheimers Dement. 2024. PMID: 37828821 Free PMC article.
ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling.
Scoyni F, Sitnikova V, Giudice L, Korhonen P, Trevisan DM, Hernandez de Sande A, Gomez-Budia M, Giniatullina R, Ugidos IF, Dhungana H, Pistono C, Korvenlaita N, Välimäki NN, Kangas SM, Hiltunen AE, Gribchenko E, Kaikkonen-Määttä MU, Koistinaho J, Ylä-Herttuala S, Hinttala R, Venø MT, Su J, Stoffel M, Schaefer A, Rajewsky N, Kjems J, LaPierre MP, Piwecka M, Jolkkonen J, Giniatullin R, Hansen TB, Malm T. Scoyni F, et al. Among authors: valimaki nn. Cell Rep. 2024 Mar 26;43(3):113862. doi: 10.1016/j.celrep.2024.113862. Epub 2024 Mar 5. Cell Rep. 2024. PMID: 38446664 Free article.