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Packaging of supplemented urokinase into naked alpha-granules of in vitro -grown megakaryocytes for targeted therapeutic delivery.
Poncz M, Zaitsev SV, Ahn H, Kowalska MA, Bdeir K, Camire RM, Cines DB, Stepanova V. Poncz M, et al. Among authors: zaitsev sv. bioRxiv [Preprint]. 2023 Dec 5:2023.12.05.570278. doi: 10.1101/2023.12.05.570278. bioRxiv. 2023. Update in: Blood Adv. 2024 Jul 23;8(14):3798-3809. doi: 10.1182/bloodadvances.2024012835 PMID: 38106191 Free PMC article. Updated. Preprint.
PAI-1 deficiency drives pulmonary vascular smooth muscle remodeling and pulmonary hypertension.
Kudryashova TV, Zaitsev SV, Jiang L, Buckley BJ, McGuckin JP, Goncharov D, Zhyvylo I, Lin D, Newcomb G, Piper B, Bogamuwa S, Saiyed A, Teos L, Pena A, Ranson M, Greenland JR, Wolters PJ, Kelso MJ, Poncz M, DeLisser HM, Cines DB, Goncharova EA, Farkas L, Stepanova V. Kudryashova TV, et al. Among authors: zaitsev sv. Am J Physiol Lung Cell Mol Physiol. 2024 Sep 1;327(3):L319-L326. doi: 10.1152/ajplung.00110.2024. Epub 2024 Jun 11. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 38860847
Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors.
Stepanova V, Dergilev KV, Holman KR, Parfyonova YV, Tsokolaeva ZI, Teter M, Atochina-Vasserman EN, Volgina A, Zaitsev SV, Lewis SP, Zabozlaev FG, Obraztsova K, Krymskaya VP, Cines DB. Stepanova V, et al. Among authors: zaitsev sv. J Biol Chem. 2017 Dec 15;292(50):20528-20543. doi: 10.1074/jbc.M117.799593. Epub 2017 Sep 27. J Biol Chem. 2017. PMID: 28972182 Free PMC article.
Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia.
Cines DB, Yarovoi SV, Zaitsev SV, Lebedeva T, Rauova L, Poncz M, Arepally GM, Khandelwal S, Stepanova V, Rux AH, Cuker A, Guo C, Ocariza LM, Travers RJ, Smith SA, Kim H, Morrissey JH, Conway EM. Cines DB, et al. Among authors: zaitsev sv. Blood Adv. 2016 Nov 22;1(1):62-74. doi: 10.1182/bloodadvances.2016000877. eCollection 2016 Nov 29. Blood Adv. 2016. PMID: 29296696 Free PMC article.
Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression.
Stepanova V, Jayaraman PS, Zaitsev SV, Lebedeva T, Bdeir K, Kershaw R, Holman KR, Parfyonova YV, Semina EV, Beloglazova IB, Tkachuk VA, Cines DB. Stepanova V, et al. Among authors: zaitsev sv. J Biol Chem. 2016 Jul 15;291(29):15029-45. doi: 10.1074/jbc.M115.678490. Epub 2016 May 4. J Biol Chem. 2016. PMID: 27151212 Free PMC article.
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