Shykind BM - Search Results

1

Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice.

Bashkirova EV, Klimpert N, Monahan K, Campbell CE, Osinski J, Tan L, Schieren I, Pourmorady A, Stecky B, Barnea G, Xie XS, Abdus-Saboor I, Shykind BM, Marlin BJ, Gronostajski RM, Fleischmann A, Lomvardas S. Bashkirova EV, et al. Among authors: shykind bm. Elife. 2023 Dec 18;12:RP87445. doi: 10.7554/eLife.87445. Elife. 2023. PMID: 38108811 Free PMC article.

2

Functional interrogation of an odorant receptor locus reveals multiple axes of transcriptional regulation.

Fleischmann A, Abdus-Saboor I, Sayed A, Shykind B. Fleischmann A, et al. PLoS Biol. 2013;11(5):e1001568. doi: 10.1371/journal.pbio.1001568. Epub 2013 May 21. PLoS Biol. 2013. PMID: 23700388 Free PMC article.

3

Gene switching and the stability of odorant receptor gene choice.

Shykind BM, Rohani SC, O'Donnell S, Nemes A, Mendelsohn M, Sun Y, Axel R, Barnea G. Shykind BM, et al. Cell. 2004 Jun 11;117(6):801-15. doi: 10.1016/j.cell.2004.05.015. Cell. 2004. PMID: 15186780 Free article.

4

Setting limits: maintaining order in a large gene family.

Abdus-Saboor I, Fleischmann A, Shykind B. Abdus-Saboor I, et al. Transcription. 2014;5(3):e28978. doi: 10.4161/trns.28978. Transcription. 2014. PMID: 25764336 Free PMC article.

5

An Expression Refinement Process Ensures Singular Odorant Receptor Gene Choice.

Abdus-Saboor I, Al Nufal MJ, Agha MV, Ruinart de Brimont M, Fleischmann A, Shykind BM. Abdus-Saboor I, et al. Among authors: shykind bm. Curr Biol. 2016 Apr 25;26(8):1083-90. doi: 10.1016/j.cub.2016.02.039. Epub 2016 Mar 31. Curr Biol. 2016. PMID: 27040780 Free article.

6

Mice with a "monoclonal nose": perturbations in an olfactory map impair odor discrimination.

Fleischmann A, Shykind BM, Sosulski DL, Franks KM, Glinka ME, Mei DF, Sun Y, Kirkland J, Mendelsohn M, Albers MW, Axel R. Fleischmann A, et al. Among authors: shykind bm. Neuron. 2008 Dec 26;60(6):1068-81. doi: 10.1016/j.neuron.2008.10.046. Neuron. 2008. PMID: 19109912 Free PMC article.

7

Olfactory deficits cause anxiety-like behaviors in mice.

Glinka ME, Samuels BA, Diodato A, Teillon J, Feng Mei D, Shykind BM, Hen R, Fleischmann A. Glinka ME, et al. Among authors: shykind bm. J Neurosci. 2012 May 9;32(19):6718-25. doi: 10.1523/JNEUROSCI.4287-11.2012. J Neurosci. 2012. PMID: 22573694 Free PMC article.

8

Regulation of odorant receptors: one allele at a time.

Shykind BM. Shykind BM. Hum Mol Genet. 2005 Apr 15;14 Spec No 1:R33-9. doi: 10.1093/hmg/ddi105. Hum Mol Genet. 2005. PMID: 15809271 Review.

9

Progranulin AAV gene therapy for frontotemporal dementia: translational studies and phase 1/2 trial interim results.

Sevigny J, Uspenskaya O, Heckman LD, Wong LC, Hatch DA, Tewari A, Vandenberghe R, Irwin DJ, Saracino D, Le Ber I, Ahmed R, Rohrer JD, Boxer AL, Boland S, Sheehan P, Brandes A, Burstein SR, Shykind BM, Kamalakaran S, Daniels CW, David Litwack E, Mahoney E, Velaga J, McNamara I, Sondergaard P, Sajjad SA, Kobayashi YM, Abeliovich A, Hefti F. Sevigny J, et al. Among authors: shykind bm. Nat Med. 2024 May;30(5):1406-1415. doi: 10.1038/s41591-024-02973-0. Epub 2024 May 14. Nat Med. 2024. PMID: 38745011 Free PMC article. Clinical Trial.

10

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

Young JM, Shykind BM, Lane RP, Tonnes-Priddy L, Ross JA, Walker M, Williams EM, Trask BJ. Young JM, et al. Among authors: shykind bm. Genome Biol. 2003;4(11):R71. doi: 10.1186/gb-2003-4-11-r71. Epub 2003 Oct 7. Genome Biol. 2003. PMID: 14611657 Free PMC article.

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