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The current toolbox for APOBEC drug discovery.
Grillo MJ, Jones KFM, Carpenter MA, Harris RS, Harki DA. Grillo MJ, et al. Trends Pharmacol Sci. 2022 May;43(5):362-377. doi: 10.1016/j.tips.2022.02.007. Trends Pharmacol Sci. 2022. PMID: 35272863 Free PMC article. Review.
Fragment-Based NMR Screening of the BPTF PHD Finger Methyl Lysine Reader Leads to the First Small-Molecule Inhibitors.
Buchholz CR, Sneddon MS, McPherson JE, Das S, Gee CT, Grillo MJ, Chai SC, Lee RE, Chen T, Harki DA, Shelat AA, Pomerantz WCK. Buchholz CR, et al. Among authors: grillo mj. ACS Med Chem Lett. 2023 Oct 3;14(10):1441-1447. doi: 10.1021/acsmedchemlett.3c00343. eCollection 2023 Oct 12. ACS Med Chem Lett. 2023. PMID: 37849548 Free PMC article.
Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders.
Tang J, Moorthy R, Hirsch LE, Demir Ö, Baker ZD, Naumann JA, Jones KFM, Grillo MJ, Haefner ES, Shi K, Levy MJ, Gupta HB, Aihara H, Harris RS, Amaro RE, Levinson NM, Harki DA. Tang J, et al. Among authors: grillo mj. Cell Chem Biol. 2025 Jan 6:S2451-9456(24)00516-6. doi: 10.1016/j.chembiol.2024.12.006. Online ahead of print. Cell Chem Biol. 2025. PMID: 39778578
Pan-Genome-Wide Association Study reveals a key role of the salmochelin receptor IroN in the biofilm formation of Salmonella Typhimurium and its monophasic variant 4,[5],12:i:
Arrieta-Gisasola A, Martínez-Ballesteros I, Martinez-Malaxetxebarria I, Garrido V, Grilló MJ, Bikandi J, Laorden L. Arrieta-Gisasola A, et al. Among authors: grillo mj. Int J Food Microbiol. 2024 Jul 16;419:110753. doi: 10.1016/j.ijfoodmicro.2024.110753. Epub 2024 May 19. Int J Food Microbiol. 2024. PMID: 38797020 Free article.
80 results