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Discovery of a structural class of antibiotics with explainable deep learning.
Wong F, Zheng EJ, Valeri JA, Donghia NM, Anahtar MN, Omori S, Li A, Cubillos-Ruiz A, Krishnan A, Jin W, Manson AL, Friedrichs J, Helbig R, Hajian B, Fiejtek DK, Wagner FF, Soutter HH, Earl AM, Stokes JM, Renner LD, Collins JJ. Wong F, et al. Among authors: omori s. Nature. 2024 Feb;626(7997):177-185. doi: 10.1038/s41586-023-06887-8. Epub 2023 Dec 20. Nature. 2024. PMID: 38123686 Free PMC article.
Deep generative design of RNA aptamers using structural predictions.
Wong F, He D, Krishnan A, Hong L, Wang AZ, Wang J, Hu Z, Omori S, Li A, Rao J, Yu Q, Jin W, Zhang T, Ilia K, Chen JX, Zheng S, King I, Li Y, Collins JJ. Wong F, et al. Among authors: omori s. Nat Comput Sci. 2024 Nov;4(11):829-839. doi: 10.1038/s43588-024-00720-6. Epub 2024 Nov 6. Nat Comput Sci. 2024. PMID: 39506080
An explainable deep learning platform for molecular discovery.
Wong F, Omori S, Li A, Krishnan A, Lach RS, Rufo J, Wilson MZ, Collins JJ. Wong F, et al. Among authors: omori s. Nat Protoc. 2024 Dec 9. doi: 10.1038/s41596-024-01084-x. Online ahead of print. Nat Protoc. 2024. PMID: 39653800 Review.
Breast mucoepidermoid carcinoma with a rare CRTC3-MAML2 fusion.
Kawaguchi K, Ijichi H, Ueo H, Hisamatsu Y, Omori S, Shigechi T, Kawaguchi K, Yamamoto H, Oda Y, Kubo M, Yoshizumi T. Kawaguchi K, et al. Among authors: omori s. Int Cancer Conf J. 2024 Aug 12;13(4):481-487. doi: 10.1007/s13691-024-00713-2. eCollection 2024 Oct. Int Cancer Conf J. 2024. PMID: 39398906
Preexisting senescent fibroblasts in the aged bladder create a tumor-permissive niche through CXCL12 secretion.
Meguro S, Johmura Y, Wang TW, Kawakami S, Tanimoto S, Omori S, Okamura YT, Hoshi S, Kayama E, Yamaguchi K, Hatakeyama S, Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Kojima Y, Nakanishi M. Meguro S, et al. Among authors: omori s. Nat Aging. 2024 Nov;4(11):1582-1597. doi: 10.1038/s43587-024-00704-1. Epub 2024 Sep 9. Nat Aging. 2024. PMID: 39251867 Free PMC article.
392 results