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Human artificial chromosome carrying R-spondin1 and IL-22 expression cassettes in rejuvenated MSCs enhances therapeutic efficacy in ulcerative colitis model mice.
Wang Y, Kazuki K, Hichiwa G, Hiratsuka M, Ogihara R, Abe S, Tu H, Li Y, Gao X, Oshimura M, Tomizuka K, Kazuki Y. Wang Y, et al. Among authors: tomizuka k. Biomed Pharmacother. 2025 Jan;182:117751. doi: 10.1016/j.biopha.2024.117751. Epub 2024 Dec 18. Biomed Pharmacother. 2025. PMID: 39693903 Free article.
Full-length human dystrophin on human artificial chromosome compensates for mouse dystrophin deficiency in a Duchenne muscular dystrophy mouse model.
Hiramuki Y, Abe S, Uno N, Kazuki K, Takata S, Miyamoto H, Takayama H, Morimoto K, Takehara S, Osaki M, Tanihata J, Takeda S, Tomizuka K, Oshimura M, Kazuki Y. Hiramuki Y, et al. Among authors: tomizuka k. Sci Rep. 2023 Mar 16;13(1):4360. doi: 10.1038/s41598-023-31481-3. Sci Rep. 2023. PMID: 36928364 Free PMC article.
Treatment of CHO cells with Taxol and reversine improves micronucleation and microcell-mediated chromosome transfer efficiency.
Uno N, Satofuka H, Miyamoto H, Honma K, Suzuki T, Yamazaki K, Ito R, Moriwaki T, Hamamichi S, Tomizuka K, Oshimura M, Kazuki Y. Uno N, et al. Among authors: tomizuka k. Mol Ther Nucleic Acids. 2023 Jul 15;33:391-403. doi: 10.1016/j.omtn.2023.07.002. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37547291 Free PMC article.
Microcell-mediated chromosome transfer between non-identical human iPSCs.
Uno N, Miyamoto H, Yamazaki K, Egawa M, Kobayashi H, Kazuki K, Osaki M, Suzuki T, Hamamichi S, Oshimura M, Tomizuka K, Kazuki Y. Uno N, et al. Among authors: tomizuka k. Mol Ther Nucleic Acids. 2024 Nov 5;35(4):102382. doi: 10.1016/j.omtn.2024.102382. eCollection 2024 Dec 10. Mol Ther Nucleic Acids. 2024. PMID: 39634136 Free PMC article.
Population-specific reference panel improves imputation quality for genome-wide association studies conducted on the Japanese population.
Flanagan J, Liu X, Ortega-Reyes D, Tomizuka K, Matoba N, Akiyama M, Koido M, Ishigaki K, Ashikawa K, Takata S, Shi M, Aoi T, Momozawa Y, Ito K, Murakami Y, Matsuda K; Biobank Japan Project; Kamatani Y, Morris AP, Horikoshi M, Terao C. Flanagan J, et al. Among authors: tomizuka k. Commun Biol. 2024 Dec 19;7(1):1665. doi: 10.1038/s42003-024-07338-4. Commun Biol. 2024. PMID: 39702642 Free PMC article.
95 results