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Impact of CRISPR/HDR-editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques.
Lee BC, Gin A, Wu C, Singh K, Grice M, Mortlock R, Abraham D, Fan X, Zhou Y, AlJanahi A, Choi U, de Ravin SS, Shin T, Hong S, Dunbar CE. Lee BC, et al. Among authors: aljanahi a. bioRxiv [Preprint]. 2023 Dec 13:2023.12.13.571396. doi: 10.1101/2023.12.13.571396. bioRxiv. 2023. Update in: Cell Stem Cell. 2024 Apr 4;31(4):455-466.e4. doi: 10.1016/j.stem.2024.02.010 PMID: 38168153 Free PMC article. Updated. Preprint.
Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia.
Kim MY, Yu KR, Kenderian SS, Ruella M, Chen S, Shin TH, Aljanahi AA, Schreeder D, Klichinsky M, Shestova O, Kozlowski MS, Cummins KD, Shan X, Shestov M, Bagg A, Morrissette JJD, Sekhri P, Lazzarotto CR, Calvo KR, Kuhns DB, Donahue RE, Behbehani GK, Tsai SQ, Dunbar CE, Gill S. Kim MY, et al. Among authors: aljanahi aa. Cell. 2018 May 31;173(6):1439-1453.e19. doi: 10.1016/j.cell.2018.05.013. Epub 2018 May 31. Cell. 2018. PMID: 29856956 Free PMC article.
An Introduction to the Analysis of Single-Cell RNA-Sequencing Data.
AlJanahi AA, Danielsen M, Dunbar CE. AlJanahi AA, et al. Mol Ther Methods Clin Dev. 2018 Aug 2;10:189-196. doi: 10.1016/j.omtm.2018.07.003. eCollection 2018 Sep 21. Mol Ther Methods Clin Dev. 2018. PMID: 30094294 Free PMC article. Review.
Prediction and validation of hematopoietic stem and progenitor cell off-target editing in transplanted rhesus macaques.
AlJanahi AA, Lazzarotto CR, Chen S, Shin TH, Cordes S, Fan X, Jabara I, Zhou Y, Young DJ, Lee BC, Yu KR, Li Y, Toms B, Tunc I, Hong SG, Truitt LL, Klermund J, Andrieux G, Kim MY, Cathomen T, Gill S, Tsai SQ, Dunbar CE. AlJanahi AA, et al. Mol Ther. 2022 Jan 5;30(1):209-222. doi: 10.1016/j.ymthe.2021.06.016. Epub 2021 Jun 24. Mol Ther. 2022. PMID: 34174439 Free PMC article.
A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions.
Shin TH, Zhou Y, Chen S, Cordes S, Grice MZ, Fan X, Lee BC, Aljanahi AA, Hong SG, Vaughan KL, Mattison JA, Kohama SG, Fabre MA, Uchida N, Demirci S, Corat MAF, Métais JY, Calvo KR, Buscarlet M, Natanson H, McGraw KL, List AF, Busque L, Tisdale JF, Vassiliou GS, Yu KR, Dunbar CE. Shin TH, et al. Among authors: aljanahi aa. Blood. 2022 Oct 20;140(16):1774-1789. doi: 10.1182/blood.2021014875. Blood. 2022. PMID: 35714307 Free PMC article.
Impact of CRISPR/HDR editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques.
Lee BC, Gin A, Wu C, Singh K, Grice M, Mortlock R, Abraham D, Fan X, Zhou Y, AlJanahi A, Choi U, DeRavin SS, Shin T, Hong S, Dunbar CE. Lee BC, et al. Among authors: aljanahi a. Cell Stem Cell. 2024 May 2;31(5):788. doi: 10.1016/j.stem.2024.04.005. Epub 2024 Apr 9. Cell Stem Cell. 2024. PMID: 38599215 Free PMC article. No abstract available.
Rhesus iPSC Safe Harbor Gene-Editing Platform for Stable Expression of Transgenes in Differentiated Cells of All Germ Layers.
Hong SG, Yada RC, Choi K, Carpentier A, Liang TJ, Merling RK, Sweeney CL, Malech HL, Jung M, Corat MAF, AlJanahi AA, Lin Y, Liu H, Tunc I, Wang X, Palisoc M, Pittaluga S, Boehm M, Winkler T, Zou J, Dunbar CE. Hong SG, et al. Among authors: aljanahi aa. Mol Ther. 2017 Jan 4;25(1):44-53. doi: 10.1016/j.ymthe.2016.10.007. Epub 2017 Jan 4. Mol Ther. 2017. PMID: 28129126 Free PMC article.
18 results