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Spatially resolved multimarker evaluation of CD274 (PD-L1)/PDCD1 (PD-1) immune checkpoint expression and macrophage polarisation in colorectal cancer.
Elomaa H, Ahtiainen M, Väyrynen SA, Ogino S, Nowak JA, Lau MC, Helminen O, Wirta EV, Seppälä TT, Böhm J, Mecklin JP, Kuopio T, Väyrynen JP. Elomaa H, et al. Among authors: seppala tt. Br J Cancer. 2023 Jun;128(11):2104-2115. doi: 10.1038/s41416-023-02238-6. Epub 2023 Mar 31. Br J Cancer. 2023. PMID: 37002343 Free PMC article.
Immunological and prognostic significance of tumour necrosis in colorectal cancer.
Kastinen M, Sirniö P, Elomaa H, Ahtiainen M, Väyrynen SA, Herzig KH, Meriläinen S, Aro R, Häivälä R, Rautio T, Saarnio J, Wirta EV, Helminen O, Seppälä TT, Kuopio T, Böhm J, Tuomisto A, Mecklin JP, Mäkinen MJ, Väyrynen JP. Kastinen M, et al. Among authors: seppala tt. Br J Cancer. 2023 Jun;128(12):2218-2226. doi: 10.1038/s41416-023-02258-2. Epub 2023 Apr 8. Br J Cancer. 2023. PMID: 37031328 Free PMC article.
Multiplexed analysis of macrophage polarisation in pulmonary metastases of microsatellite stable colorectal cancer.
Karjula T, Elomaa H, Väyrynen SA, Kuopio T, Ahtiainen M, Mustonen O, Puro I, Niskakangas A, Mecklin JP, Böhm J, Wirta EV, Seppälä TT, Sihvo E, Yannopoulos F, Helminen O, Väyrynen JP. Karjula T, et al. Among authors: seppala tt. Cancer Immunol Immunother. 2024 Feb 22;73(3):59. doi: 10.1007/s00262-024-03646-0. Cancer Immunol Immunother. 2024. PMID: 38386105 Free PMC article.
The prognostic role of tumor budding and tumor-stroma ratio in pulmonary metastasis of colorectal carcinoma.
Karjula T, Kemi N, Niskakangas A, Mustonen O, Puro I, Pohjanen VM, Kuopio T, Elomaa H, Ahtiainen M, Mecklin JP, Seppälä TT, Wirta EV, Sihvo E, Väyrynen JP, Yannopoulos F, Helminen O. Karjula T, et al. Among authors: seppala tt. Eur J Surg Oncol. 2023 Jul;49(7):1298-1306. doi: 10.1016/j.ejso.2023.02.009. Epub 2023 Feb 21. Eur J Surg Oncol. 2023. PMID: 36841693 Free article.
Circulating metabolome landscape in Lynch syndrome.
Jokela TA, Karppinen JE, Kärkkäinen M, Mecklin JP, Walker S, Seppälä TT, Laakkonen EK. Jokela TA, et al. Among authors: seppala tt. Cancer Metab. 2024 Feb 5;12(1):4. doi: 10.1186/s40170-024-00331-9. Cancer Metab. 2024. PMID: 38317210 Free PMC article.
Updated European guidelines for clinical management of familial adenomatous polyposis (FAP), MUTYH-associated polyposis (MAP), gastric adenocarcinoma, proximal polyposis of the stomach (GAPPS) and other rare adenomatous polyposis syndromes: a joint EHTG-ESCP revision.
Zaffaroni G, Mannucci A, Koskenvuo L, de Lacy B, Maffioli A, Bisseling T, Half E, Cavestro GM, Valle L, Ryan N, Aretz S, Brown K, Buttitta F, Carneiro F, Claber O, Blanco-Colino R, Collard M, Crosbie E, Cunha M, Doulias T, Fleming C, Heinrich H, Hüneburg R, Metras J, Nagtegaal I, Negoi I, Nielsen M, Pellino G, Ricciardiello L, Sagir A, Sánchez-Guillén L, Seppälä TT, Siersema P, Striebeck B, Sampson JR, Latchford A, Parc Y, Burn J, Möslein G. Zaffaroni G, et al. Among authors: seppala tt. Br J Surg. 2024 May 3;111(5):znae070. doi: 10.1093/bjs/znae070. Br J Surg. 2024. PMID: 38722804 Free PMC article.
Establishing Criteria for Tumor Necrosis as Prognostic Indicator in Colorectal Cancer.
Kastinen M, Sirniö P, Elomaa H, Äijälä VK, Karjalainen H, Tapiainen VV, Pohjanen VM, Kemppainen J, Sliashynskaya K, Ahtiainen M, Rintala J, Meriläinen S, Rautio T, Saarnio J, Mattila TT, Lindgren O, Wirta EV, Helminen O, Seppälä TT, Böhm J, Mecklin JP, Tuomisto A, Mäkinen MJ, Väyrynen JP. Kastinen M, et al. Among authors: seppala tt. Am J Surg Pathol. 2024 Oct 1;48(10):1284-1292. doi: 10.1097/PAS.0000000000002286. Epub 2024 Jul 15. Am J Surg Pathol. 2024. PMID: 39004843 Free PMC article.
Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines.
Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Seppälä TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A, Guillem JG, Houwen BBSL, Kahi C, Kalady MF, Kastrinos F, Kühn F, Laghi L, Latchford A, Liska D, Lynch P, Malesci A, Mauri G, Meldolesi E, Møller P, Monahan KJ, Möslein G, Murphy CC, Nass K, Ng K, Oliani C, Papaleo E, Patel SG, Puzzono M, Remo A, Ricciardiello L, Ripamonti CI, Siena S, Singh SK, Stadler ZK, Stanich PP, Syngal S, Turi S, Urso ED, Valle L, Vanni VS, Vilar E, Vitellaro M, You YN, Yurgelun MB, Zuppardo RA, Stoffel EM; Associazione Italiana Familiarità Ereditarietà Tumori; Collaborative Group of the Americas on Inherited Gastrointestinal Cancer; European Hereditary Tumour Group, and the International Society for Gastrointestinal Hereditary Tumours. Cavestro GM, et al. Among authors: seppala tt. Clin Gastroenterol Hepatol. 2023 Mar;21(3):581-603.e33. doi: 10.1016/j.cgh.2022.12.006. Epub 2022 Dec 20. Clin Gastroenterol Hepatol. 2023. PMID: 36549470 Free PMC article.
86 results