Driscoll M - Search Results

1

Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons.

Yang Y, Arnold ML, Lange CM, Sun LH, Broussalian M, Doroodian S, Ebata H, Choy EH, Poon K, Moreno TM, Singh A, Driscoll M, Kumsta C, Hansen M. Yang Y, et al. Among authors: driscoll m. Nat Aging. 2024 Feb;4(2):198-212. doi: 10.1038/s43587-023-00548-1. Epub 2024 Jan 4. Nat Aging. 2024. PMID: 38177330 Free PMC article.

2

A transmembrane domain of the putative channel subunit MEC-4 influences mechanotransduction and neurodegeneration in C. elegans.

Hong K, Driscoll M. Hong K, et al. Among authors: driscoll m. Nature. 1994 Feb 3;367(6462):470-3. doi: 10.1038/367470a0. Nature. 1994. PMID: 8107806

3

A role for autophagy in the extension of lifespan by dietary restriction in C. elegans.

Hansen M, Chandra A, Mitic LL, Onken B, Driscoll M, Kenyon C. Hansen M, et al. Among authors: driscoll m. PLoS Genet. 2008 Feb;4(2):e24. doi: 10.1371/journal.pgen.0040024. PLoS Genet. 2008. PMID: 18282106 Free PMC article.

4

C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress.

Melentijevic I, Toth ML, Arnold ML, Guasp RJ, Harinath G, Nguyen KC, Taub D, Parker JA, Neri C, Gabel CV, Hall DH, Driscoll M. Melentijevic I, et al. Among authors: driscoll m. Nature. 2017 Feb 16;542(7641):367-371. doi: 10.1038/nature21362. Epub 2017 Feb 8. Nature. 2017. PMID: 28178240 Free PMC article.

5

Q&A: Trash talk: disposal and remote degradation of neuronal garbage.

Arnold ML, Melentijevic I, Smart AJ, Driscoll M. Arnold ML, et al. Among authors: driscoll m. BMC Biol. 2018 Jan 30;16(1):17. doi: 10.1186/s12915-018-0487-6. BMC Biol. 2018. PMID: 29382333 Free PMC article. Review.

6

Quantitative Approaches for Scoring in vivo Neuronal Aggregate and Organelle Extrusion in Large Exopher Vesicles in C. elegans.

Arnold ML, Cooper J, Grant BD, Driscoll M. Arnold ML, et al. Among authors: driscoll m. J Vis Exp. 2020 Sep 18;(163):10.3791/61368. doi: 10.3791/61368. J Vis Exp. 2020. PMID: 33016946 Free PMC article.

7

Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling.

Cooper JF, Guasp RJ, Arnold ML, Grant BD, Driscoll M. Cooper JF, et al. Among authors: driscoll m. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2101410118. doi: 10.1073/pnas.2101410118. Proc Natl Acad Sci U S A. 2021. PMID: 34475208 Free PMC article.

8

Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell.

Wang Y, Arnold ML, Smart AJ, Wang G, Androwski RJ, Morera A, Nguyen KCQ, Schweinsberg PJ, Bai G, Cooper J, Hall DH, Driscoll M, Grant BD. Wang Y, et al. Among authors: driscoll m. Elife. 2023 Mar 2;12:e82227. doi: 10.7554/eLife.82227. Elife. 2023. PMID: 36861960 Free PMC article.

9

Intermediate filaments associate with aggresome-like structures in proteostressed C. elegans neurons and influence large vesicle extrusions as exophers.

Arnold ML, Cooper J, Androwski R, Ardeshna S, Melentijevic I, Smart J, Guasp RJ, Nguyen KCQ, Bai G, Hall DH, Grant BD, Driscoll M. Arnold ML, et al. Among authors: driscoll m. Nat Commun. 2023 Jul 24;14(1):4450. doi: 10.1038/s41467-023-39700-1. Nat Commun. 2023. PMID: 37488107 Free PMC article.

10

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background.

Banse SA, Jackson EG, Sedore CA, Onken B, Hall D, Coleman-Hulbert A, Huynh P, Garrett T, Johnson E, Harinath G, Inman D, Guo S, Morshead M, Xue J, Falkowski R, Chen E, Herrera C, Kirsch AJ, Perez VI, Guo M, Lithgow GJ, Driscoll M, Phillips PC. Banse SA, et al. Among authors: driscoll m. Aging (Albany NY). 2024 Apr 12;16(7):5829-5855. doi: 10.18632/aging.205743. Epub 2024 Apr 12. Aging (Albany NY). 2024. PMID: 38613792 Free PMC article.

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