Fan G - Search Results

1

THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development.

Zhang J, Jiang Z, Zhang X, Yang Z, Wang J, Chen J, Chen L, Song M, Zhang Y, Huang M, Chen S, Xiong X, Wang Y, Hao P, Horng T, Zhuang M, Zhang L, Zuo E, Bai F, Zheng J, Wang H, Fan G. Zhang J, et al. Among authors: fan g. Nat Struct Mol Biol. 2024 Jan;31(1):54-67. doi: 10.1038/s41594-023-01131-3. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177672

2

Key elements for designing and performing a CRISPR/Cas9-based genetic screen.

Shang W, Wang F, Fan G, Wang H. Shang W, et al. Among authors: fan g. J Genet Genomics. 2017 Sep 20;44(9):439-449. doi: 10.1016/j.jgg.2017.09.005. Epub 2017 Sep 22. J Genet Genomics. 2017. PMID: 28967615 Review.

3

Spatial regulation of signaling by the coordinated action of the protein tyrosine kinases MET and FER.

Zhang J, Wang Z, Zhang S, Chen Y, Xiong X, Li X, Tonks NK, Fan G. Zhang J, et al. Among authors: fan g. Cell Signal. 2018 Oct;50:100-110. doi: 10.1016/j.cellsig.2018.06.006. Epub 2018 Jun 18. Cell Signal. 2018. PMID: 29920310 Free PMC article.

4

Protein tyrosine phosphatase receptor type R (PTPRR) antagonizes the Wnt signaling pathway in ovarian cancer by dephosphorylating and inactivating β-catenin.

Wang Y, Cao J, Liu W, Zhang J, Wang Z, Zhang Y, Hou L, Chen S, Hao P, Zhang L, Zhuang M, Yu Y, Li D, Fan G. Wang Y, et al. Among authors: fan g. J Biol Chem. 2019 Nov 29;294(48):18306-18323. doi: 10.1074/jbc.RA119.010348. Epub 2019 Oct 25. J Biol Chem. 2019. PMID: 31653698 Free PMC article.

5

CRISPR system: Discovery, development and off-target detection.

Chen S, Yao Y, Zhang Y, Fan G. Chen S, et al. Among authors: fan g. Cell Signal. 2020 Jun;70:109577. doi: 10.1016/j.cellsig.2020.109577. Epub 2020 Feb 22. Cell Signal. 2020. PMID: 32097710 Review.

6

NAD⁺ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells.

Wang Y, Wang F, Wang L, Qiu S, Yao Y, Yan C, Xiong X, Chen X, Ji Q, Cao J, Gao G, Li D, Zhang L, Guo Z, Wang R, Wang H, Fan G. Wang Y, et al. Among authors: fan g. Cell Rep. 2021 Aug 10;36(6):109516. doi: 10.1016/j.celrep.2021.109516. Cell Rep. 2021. PMID: 34380043 Free article.

7

FER-mediated phosphorylation and PIK3R2 recruitment on IRS4 promotes AKT activation and tumorigenesis in ovarian cancer cells.

Zhang Y, Xiong X, Zhu Q, Zhang J, Chen S, Wang Y, Cao J, Chen L, Hou L, Zhao X, Hao P, Chen J, Zhuang M, Li D, Fan G. Zhang Y, et al. Among authors: fan g. Elife. 2022 May 12;11:e76183. doi: 10.7554/eLife.76183. Elife. 2022. PMID: 35550247 Free PMC article.

8

Development of the nonreceptor tyrosine kinase FER-targeting PROTACs as a potential strategy for antagonizing ovarian cancer cell motility and invasiveness.

Zhang Y, Xiong X, Sun R, Zhu X, Wang C, Jiang B, Yang X, Li D, Fan G. Zhang Y, et al. Among authors: fan g. J Biol Chem. 2023 Jun;299(6):104825. doi: 10.1016/j.jbc.2023.104825. Epub 2023 May 16. J Biol Chem. 2023. PMID: 37196766 Free PMC article.

9

PINX1 loss confers susceptibility to PARP inhibition in pan-cancer cells.

Huang M, Zhu X, Wang C, He L, Li L, Wang H, Fan G, Wang Y. Huang M, et al. Among authors: fan g. Cell Death Dis. 2024 Aug 22;15(8):610. doi: 10.1038/s41419-024-07009-6. Cell Death Dis. 2024. PMID: 39174499 Free PMC article.

10

Minimizing DNA trapping while maintaining activity inhibition via selective PARP1 degrader.

Chen L, Zou Y, Sun R, Huang M, Zhu X, Tang X, Yang X, Li D, Fan G, Wang Y. Chen L, et al. Among authors: fan g. Cell Death Dis. 2024 Dec 18;15(12):898. doi: 10.1038/s41419-024-07277-2. Cell Death Dis. 2024. PMID: 39695097 Free PMC article.

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