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METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastoma.
Vaid R, Thombare K, Mendez A, Burgos-Panadero R, Djos A, Jachimowicz D, Lundberg KI, Bartenhagen C, Kumar N, Tümmler C, Sihlbom C, Fransson S, Johnsen JI, Kogner P, Martinsson T, Fischer M, Mondal T. Vaid R, et al. Among authors: mendez a. Nucleic Acids Res. 2024 Mar 21;52(5):2648-2671. doi: 10.1093/nar/gkad1242. Nucleic Acids Res. 2024. PMID: 38180812 Free PMC article.
METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma.
Thombare K, Vaid R, Pucci P, Ihrmark Lundberg K, Ayyalusamy R, Baig MH, Mendez A, Burgos-Panadero R, Höppner S, Bartenhagen C, Sjövall D, Rehan AA, Dattatraya Nale S, Djos A, Martinsson T, Jaako P, Dong JJ, Kogner P, Johnsen JI, Fischer M, Turner SD, Mondal T. Thombare K, et al. Among authors: mendez a. EMBO J. 2024 Dec;43(24):6310-6335. doi: 10.1038/s44318-024-00299-8. Epub 2024 Nov 11. EMBO J. 2024. PMID: 39528654 Free PMC article.
Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer.
Ganguli P, Basanta CC, Acha-Sagredo A, Misetic H, Armero M, Mendez A, Zahra A, Devonshire G, Kelly G, Freeman A, Green M, Nye E, Bichisecchi A, Bonfanti P; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium; Rodriguez-Justo M, Spencer J, Fitzgerald RC, Ciccarelli FD. Ganguli P, et al. Among authors: mendez a. Nat Cancer. 2025 Jan 3. doi: 10.1038/s43018-024-00876-0. Online ahead of print. Nat Cancer. 2025. PMID: 39753721
Structure of Plasmodium vivaxN-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy.
Mendez A, Bolling C, Taylor S, Makumire S, Staker B, Reers A, Hammerson B, Mayclin SJ, Abendroth J, Lorimer DD, Edwards TE, Tate EW, Subramanian S, Bell AS, Myler PJ, Asojo OA, Chakafana G. Mendez A, et al. Acta Crystallogr F Struct Biol Commun. 2025 Jan 1;81(Pt 1):1-10. doi: 10.1107/S2053230X24011348. Epub 2025 Jan 1. Acta Crystallogr F Struct Biol Commun. 2025. PMID: 39655507 Free PMC article.
981 results