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Rescuing Photoreceptors in RPE Dysfunction-Driven Retinal Degeneration: The Role of Small Extracellular Vesicles Secreted from Retinal Pigment Epithelium.
Pollalis D, Georgescu C, Wren JD, Tombulyan G, Leung JM, Lo PA, Bloemhof CM, Lee RH, Bae E, Bailey JK, Pennington BO, Khan AI, Kelly KR, Yeh AK, Sundaram KS, Humayun M, Louie S, Clegg DO, Lee SY. Pollalis D, et al. Among authors: wren jd. bioRxiv [Preprint]. 2024 Apr 13:2024.04.09.588773. doi: 10.1101/2024.04.09.588773. bioRxiv. 2024. PMID: 38645051 Free PMC article. Preprint.
The nitrone compound OKN-007 delays motor neuron loss and disease progression in the G93A mouse model of amyotrophic lateral sclerosis.
Bhaskaran S, Piekarz KM, Brown J, Yang B, Ocañas SR, Wren JD, Georgescu C, Bottoms C, Murphy A, Thomason J, Saunders D, Smith N, Towner R, Van Remmen H. Bhaskaran S, et al. Among authors: wren jd. Front Neurosci. 2024 Nov 20;18:1505369. doi: 10.3389/fnins.2024.1505369. eCollection 2024. Front Neurosci. 2024. PMID: 39633896 Free PMC article.
Dynamics of microRNA secreted via extracellular vesicles during the maturation of embryonic stem cell-derived retinal pigment epithelium.
Pollalis D, Nair GKG, Leung J, Bloemhof CM, Bailey JK, Pennington BO, Kelly KR, Khan AI, Yeh AK, Sundaram KS, Clegg DO, Peng CC, Xu L, Georgescu C, Wren JD, Lee SY. Pollalis D, et al. Among authors: wren jd. J Extracell Biol. 2024 Sep 13;3(9):e70001. doi: 10.1002/jex2.70001. eCollection 2024 Sep. J Extracell Biol. 2024. PMID: 39281021 Free PMC article.
CD151 Maintains Endolysosomal Protein Quality to Inhibit Vascular Inflammation.
Chen J, Ding Y, Jiang C, Qu R, Wren JD, Georgescu C, Wang X, Reuter DN, Liu B, Giles CB, Mayr CH, Schiller HB, Dai J, Stipp CS, Subramaniyan B, Wang J, Zuo H, Huang C, Fung KM, Rice HC, Sonnenberg A, Wu D, Walters MS, Zhao YY, Kanie T, Hays FA, Papin JF, Wang DW, Zhang XA. Chen J, et al. Among authors: wren jd. Circ Res. 2024 May 10;134(10):1330-1347. doi: 10.1161/CIRCRESAHA.123.323190. Epub 2024 Apr 1. Circ Res. 2024. PMID: 38557119
Absence of Either Ripk3 or Mlkl Reduces Incidence of Hepatocellular Carcinoma Independent of Liver Fibrosis.
Mohammed S, Thadathil N, Ohene-Marfo P, Tran AL, Van Der Veldt M, Georgescu C, Oh S, Nicklas EH, Wang D, Haritha NH, Luo W, Janknecht R, Miller BF, Wren JD, Freeman WM, Deepa SS. Mohammed S, et al. Among authors: wren jd. Mol Cancer Res. 2023 Sep 1;21(9):933-946. doi: 10.1158/1541-7786.MCR-22-0820. Mol Cancer Res. 2023. PMID: 37204757 Free PMC article.
217 results