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Page 1
Androgen receptor drives polyamine synthesis creating a vulnerability for prostate cancer.
Kumar R, Jonnatan S, Sanin DE, Vakkala V, Kadam A, Kumar S, Dalrymple SL, Zhao L, Foley J, Holbert CE, Nwafor A, Kittane S, Penner E, Apostolova P, Warner S, Dang CV, Toska E, Thompson EA, Isaacs JT, De Marzo AM, Pearce EL, Stewart TM, Casero RA, Denmeade SR, Sena LA. Kumar R, et al. Among authors: sanin de. medRxiv [Preprint]. 2024 Dec 13:2024.12.12.24318845. doi: 10.1101/2024.12.12.24318845. medRxiv. 2024. PMID: 39711733 Free PMC article. Preprint.
High mitochondrial DNA levels accelerate lung adenocarcinoma progression.
Mennuni M, Wilkie SE, Michon P, Alsina D, Filograna R, Lindberg M, Sanin DE, Rosenberger F, Schaaf A, Larsson E, Pearce EL, Larsson NG. Mennuni M, et al. Among authors: sanin de. Sci Adv. 2024 Nov;10(44):eadp3481. doi: 10.1126/sciadv.adp3481. Epub 2024 Nov 1. Sci Adv. 2024. PMID: 39485842 Free PMC article.
Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment.
Villa M, Sanin DE, Apostolova P, Corrado M, Kabat AM, Cristinzio C, Regina A, Carrizo GE, Rana N, Stanczak MA, Baixauli F, Grzes KM, Cupovic J, Solagna F, Hackl A, Globig AM, Hässler F, Puleston DJ, Kelly B, Cabezas-Wallscheid N, Hasselblatt P, Bengsch B, Zeiser R, Sagar, Buescher JM, Pearce EJ, Pearce EL. Villa M, et al. Among authors: sanin de. Nat Commun. 2024 Jan 11;15(1):451. doi: 10.1038/s41467-024-44689-2. Nat Commun. 2024. PMID: 38200005 Free PMC article.
Bipolar androgen therapy plus nivolumab for patients with metastatic castration-resistant prostate cancer: the COMBAT phase II trial.
Markowski MC, Taplin ME, Aggarwal R, Sena LA, Wang H, Qi H, Lalji A, Sinibaldi V, Carducci MA, Paller CJ, Marshall CH, Eisenberger MA, Sanin DE, Yegnasubramanian S, Gomes-Alexandre C, Ozbek B, Jones T, De Marzo AM, Denmeade SR, Antonarakis ES. Markowski MC, et al. Among authors: sanin de. Nat Commun. 2024 Jan 2;15(1):14. doi: 10.1038/s41467-023-44514-2. Nat Commun. 2024. PMID: 38167882 Free PMC article. Clinical Trial.
Metabolic and functional remodeling of colonic macrophages in response to high-fat diet-induced obesity.
Castoldi A, Sanin DE, van Teijlingen Bakker N, Aguiar CF, de Brito Monteiro L, Rana N, Grzes KM, Kabat AM, Curtis J, Cameron AM, Caputa G, Antônio de Souza T, Souto FO, Buescher JM, Edwards-Hicks J, Pearce EL, Pearce EJ, Saraiva Camara NO. Castoldi A, et al. Among authors: sanin de. iScience. 2023 Aug 25;26(10):107719. doi: 10.1016/j.isci.2023.107719. eCollection 2023 Oct 20. iScience. 2023. PMID: 37674984 Free PMC article.
Prostaglandin E 2 controls the metabolic adaptation of T cells to the intestinal microenvironment.
Villa M, Sanin DE, Apostolova P, Corrado M, Kabat AM, Cristinzio C, Regina A, Carrizo GE, Rana N, Stanczak MA, Baixauli F, Grzes KM, Cupovic J, Solagna F, Hackl A, Globig AM, Hässler F, Puleston DJ, Kelly B, Cabezas-Wallscheid N, Hasselblatt P, Bengsch B, Zeiser R, Sagar, Buescher JM, Pearce EJ, Pearce EL. Villa M, et al. Among authors: sanin de. bioRxiv [Preprint]. 2023 Mar 15:2023.03.13.532431. doi: 10.1101/2023.03.13.532431. bioRxiv. 2023. Update in: Nat Commun. 2024 Jan 11;15(1):451. doi: 10.1038/s41467-024-44689-2 PMID: 36993703 Free PMC article. Updated. Preprint.
Phosphoinositide acyl chain saturation drives CD8+ effector T cell signaling and function.
Edwards-Hicks J, Apostolova P, Buescher JM, Maib H, Stanczak MA, Corrado M, Klein Geltink RI, Maccari ME, Villa M, Carrizo GE, Sanin DE, Baixauli F, Kelly B, Curtis JD, Haessler F, Patterson A, Field CS, Caputa G, Kyle RL, Soballa M, Cha M, Paul H, Martin J, Grzes KM, Flachsmann L, Mitterer M, Zhao L, Winkler F, Rafei-Shamsabadi DA, Meiss F, Bengsch B, Zeiser R, Puleston DJ, O'Sullivan D, Pearce EJ, Pearce EL. Edwards-Hicks J, et al. Among authors: sanin de. Nat Immunol. 2023 Mar;24(3):516-530. doi: 10.1038/s41590-023-01419-y. Epub 2023 Feb 2. Nat Immunol. 2023. PMID: 36732424 Free PMC article.
49 results