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Page 1
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases.
Wang L, Bohmer MJ, Wang J, Nardella F, Calla J, Laureano De Souza M, Schindler KA, Montejo L, Mittal N, Rocamora F, Treat M, Charlton JT, Tumwebaze PK, Rosenthal PJ, Cooper RA, Chakrabarti R, Winzeler EA, Chakrabarti D, Gray NS. Wang L, et al. Among authors: nardella f. J Med Chem. 2024 Jan 25;67(2):1460-1480. doi: 10.1021/acs.jmedchem.3c02046. Epub 2024 Jan 12. J Med Chem. 2024. PMID: 38214254
Understanding the Antiplasmodial Action of Resistance-Refractory Xanthoquinodin A1.
Collins JE, Jiang T, Lee JW, Wendt K, Nardella F, Jeon J, Paes R, Santos NM, Rocamora F, Chang M, Schaefer S, Cichewicz RH, Winzeler EA, Chakrabarti D. Collins JE, et al. Among authors: nardella f. ACS Infect Dis. 2024 Jun 14;10(6):2276-2287. doi: 10.1021/acsinfecdis.4c00232. Epub 2024 May 29. ACS Infect Dis. 2024. PMID: 38810215
Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum.
Nardella F, Dobrescu I, Hassan H, Rodrigues F, Thiberge S, Mancio-Silva L, Tafit A, Jallet C, Cadet-Daniel V, Goussin S, Lorthiois A, Menon Y, Molinier N, Pechalrieu D, Long C, Sautel F, Matondo M, Duchateau M, Médard G, Witkowski B, Scherf A, Halby L, Arimondo PB. Nardella F, et al. iScience. 2023 Jan 11;26(2):105940. doi: 10.1016/j.isci.2023.105940. eCollection 2023 Feb 17. iScience. 2023. PMID: 36718363 Free PMC article.
53 results