Kirschning A - Search Results

1

Is Simultaneous Binding to DNA and Gyrase Important for the Antibacterial Activity of Cystobactamids?

Solga D, Wieske LHE, Wilcox S, Zeilinger C, Jansen-Olliges L, Cirnski K, Herrmann J, Müller R, Erdelyi M, Kirschning A. Solga D, et al. Among authors: kirschning a. Chemistry. 2024 Apr 2;30(19):e202303796. doi: 10.1002/chem.202303796. Epub 2024 Feb 15. Chemistry. 2024. PMID: 38217886

2

Chemoenzymatic Synthesis of a New Germacrene Derivative Named Germacrene F.

Struwe H, Droste J, Dhar D, Davari MD, Kirschning A. Struwe H, et al. Among authors: kirschning a. Chembiochem. 2024 Jan 2;25(1):e202300599. doi: 10.1002/cbic.202300599. Epub 2023 Nov 20. Chembiochem. 2024. PMID: 37910783

3

Heinz-Günter Floss (1934-2022).

Müller M, Kirschning A. Müller M, et al. Among authors: kirschning a. Angew Chem Int Ed Engl. 2023 Aug 1;62(31):e202305459. doi: 10.1002/anie.202305459. Epub 2023 Jul 18. Angew Chem Int Ed Engl. 2023. PMID: 37464956

4

Evolution at the Origins of Life?

Schoenmakers LLJ, Reydon TAC, Kirschning A. Schoenmakers LLJ, et al. Among authors: kirschning a. Life (Basel). 2024 Jan 24;14(2):175. doi: 10.3390/life14020175. Life (Basel). 2024. PMID: 38398684 Free PMC article. Review.

5

Chemoenzymatic Formation of Oxa-Terpenoids by Sesqui- and Diterpene Synthase-Mediated Biotransformations with 9-Oxy-FPP Ether Derivatives.

Struwe H, Nguyen T, Schwörer S, Droste J, Spinck H, Kirschning A. Struwe H, et al. Among authors: kirschning a. Biochemistry. 2024 Dec 28. doi: 10.1021/acs.biochem.4c00589. Online ahead of print. Biochemistry. 2024. PMID: 39731539

6

Synthetic studies on the tetrasubstituted D-ring of cystobactamids lead to potent terephthalic acid antibiotics.

Stappert M, Kohnhäuser D, Seedorf T, Coetzee J, Rox K, Fuchs HLS, Cirnski K, Leitner C, Herrmann J, Kirschning A, Müller R, Brönstrup M. Stappert M, et al. Among authors: kirschning a. Commun Chem. 2024 Nov 5;7(1):252. doi: 10.1038/s42004-024-01337-6. Commun Chem. 2024. PMID: 39501041 Free PMC article.

7

Optimization of the Central α-Amino Acid in Cystobactamids to the Broad-Spectrum, Resistance-Breaking Antibiotic CN-CC-861.

Kohnhäuser D, Seedorf T, Cirnski K, Heimann D, Coetzee J, Sordello S, Richter J, Stappert M, Sabuco JF, Corbett D, Bacqué E, Rox K, Herrmann J, Vassort A, Müller R, Kirschning A, Brönstrup M. Kohnhäuser D, et al. Among authors: kirschning a. J Med Chem. 2024 Oct 10;67(19):17162-17190. doi: 10.1021/acs.jmedchem.4c00927. Epub 2024 Sep 20. J Med Chem. 2024. PMID: 39303218 Free PMC article.

8

Telescoping a Prenyltransferase and a Diterpene Synthase to Transform Unnatural FPP Derivatives to Diterpenoids.

Struwe H, Li H, Schrödter F, Höft L, Fohrer J, Dickschat JS, Kirschning A. Struwe H, et al. Among authors: kirschning a. Org Lett. 2024 Jul 19;26(28):5888-5892. doi: 10.1021/acs.orglett.4c01670. Epub 2024 Jul 8. Org Lett. 2024. PMID: 38976793 Free PMC article.

9

Sesquiterpene Cyclase BcBOT2 Promotes the Unprecedented Wagner-Meerwein Rearrangement of the Methoxy Group.

Moeller M, Dhar D, Dräger G, Özbasi M, Struwe H, Wildhagen M, Davari MD, Beutel S, Kirschning A. Moeller M, et al. Among authors: kirschning a. J Am Chem Soc. 2024 Jul 3;146(26):17838-17846. doi: 10.1021/jacs.4c03386. Epub 2024 Jun 18. J Am Chem Soc. 2024. PMID: 38888422 Free PMC article.

10

Why pyridoxal phosphate could be a functional predecessor of thiamine pyrophosphate and speculations on a primordial metabolism.

Kirschning A. Kirschning A. RSC Chem Biol. 2024 Apr 18;5(6):508-517. doi: 10.1039/d4cb00016a. eCollection 2024 Jun 5. RSC Chem Biol. 2024. PMID: 38846080 Free PMC article. Review.

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