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21 results

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Page 1
ABCG1 orchestrates adipose tissue macrophage plasticity and insulin resistance in obesity by rewiring saturated fatty acid pools.
Dahik VD, Kc P, Materne C, Reydellet C, Lhomme M, Cruciani-Guglielmacci C, Denom J, Bun E, Ponnaiah M, Deknuydt F, Frisdal E, Hardy LM, Durand H, Guillas I, Lesnik P, Gudelj I, Lauc G, Guérin M, Kontush A, Soprani A, Magnan C, Diedisheim M, Bluteau O, Venteclef N, Le Goff W. Dahik VD, et al. Among authors: denom j. Sci Transl Med. 2024 Dec 11;16(777):eadi6682. doi: 10.1126/scitranslmed.adi6682. Epub 2024 Dec 11. Sci Transl Med. 2024. PMID: 39661702
A multiorgan map of metabolic, signaling, and inflammatory pathways that coordinately control fasting glycemia in mice.
Mehl F, Sánchez-Archidona AR, Meitil I, Gerl M, Cruciani-Guglielmacci C, Wigger L, Le Stunff H, Meneyrol K, Lallement J, Denom J, Klose C, Simons K, Pagni M, Magnan C, Ibberson M, Thorens B. Mehl F, et al. Among authors: denom j. iScience. 2024 Oct 11;27(11):111134. doi: 10.1016/j.isci.2024.111134. eCollection 2024 Nov 15. iScience. 2024. PMID: 39507247 Free PMC article.
A neuronal circuit driven by GLP-1 in the olfactory bulb regulates insulin secretion.
Montaner M, Denom J, Simon V, Jiang W, Holt MK, Brierley DI, Rouch C, Foppen E, Kassis N, Jarriault D, Khan D, Eygret L, Mifsud F, Hodson DJ, Broichhagen J, Van Oudenhove L, Fioramonti X, Gault V, Cota D, Reimann F, Gribble FM, Migrenne-Li S, Trapp S, Gurden H, Magnan C. Montaner M, et al. Among authors: denom j. Nat Commun. 2024 Aug 13;15(1):6941. doi: 10.1038/s41467-024-51076-4. Nat Commun. 2024. PMID: 39138162 Free PMC article.
Interesterified palm oil promotes insulin resistance and altered insulin secretion and signaling in Swiss mice.
Dos Santos RM, Miyamoto JÉ, Siqueira BP, Araujo TR, Vettorazzi JF, Menta PLR, Denom J, Latorraca MQ, Cruciani-Guglielmacci C, Carneiro EM, Torsoni A, Torsoni M, Badan AP, Magnan C, Le Stunff H, Ignácio-Souza L, Milanski M. Dos Santos RM, et al. Among authors: denom j. Food Res Int. 2024 Feb;177:113850. doi: 10.1016/j.foodres.2023.113850. Epub 2023 Dec 16. Food Res Int. 2024. PMID: 38225125
PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption.
Ladraa S, Zerbib L, Bayard C, Fraissenon A, Venot Q, Morin G, Garneau AP, Isnard P, Chapelle C, Hoguin C, Fraitag S, Duong JP, Guibaud L, Besançon A, Kaltenbach S, Villarese P, Asnafi V, Broissand C, Goudin N, Dussiot M, Nemazanyy I, Viel T, Autret G, Cruciani-Guglielmacci C, Denom J, Bruneau J, Tavitian B, Legendre C, Dairou J, Lacorte JM, Levy P, Pende M, Polak M, Canaud G. Ladraa S, et al. Among authors: denom j. Sci Adv. 2022 Dec 9;8(49):eade7823. doi: 10.1126/sciadv.ade7823. Epub 2022 Dec 9. Sci Adv. 2022. PMID: 36490341 Free PMC article.
Regenerating islet-derived protein 3α: A promising therapy for diabetes. Preliminary data in rodents and in humans.
Le Lay A, Philippe E, Roth F, Sanchez-Archidona AR, Mehl F, Denom J, Prasad R, Asplund O, Hansson O, Ibberson M, Andreelli F, Santoro L, Amouyal P, Amouyal G, Brechot C, Jamot L, Cruciani-Guglielmacci C, Magnan C. Le Lay A, et al. Among authors: denom j. Heliyon. 2022 Jul 16;8(7):e09944. doi: 10.1016/j.heliyon.2022.e09944. eCollection 2022 Jul. Heliyon. 2022. PMID: 35874080 Free PMC article.
Homocysteine Metabolism Pathway Is Involved in the Control of Glucose Homeostasis: A Cystathionine Beta Synthase Deficiency Study in Mouse.
Cruciani-Guglielmacci C, Meneyrol K, Denom J, Kassis N, Rachdi L, Makaci F, Migrenne-Li S, Daubigney F, Georgiadou E, Denis RG, Rodriguez Sanchez-Archidona A, Paul JL, Thorens B, Rutter GA, Magnan C, Le Stunff H, Janel N. Cruciani-Guglielmacci C, et al. Among authors: denom j. Cells. 2022 May 25;11(11):1737. doi: 10.3390/cells11111737. Cells. 2022. PMID: 35681432 Free PMC article.
Plasma triacylglycerols are biomarkers of β-cell function in mice and humans.
Sánchez-Archidona AR, Cruciani-Guglielmacci C, Roujeau C, Wigger L, Lallement J, Denom J, Barovic M, Kassis N, Mehl F, Weitz J, Distler M, Klose C, Simons K, Ibberson M, Solimena M, Magnan C, Thorens B. Sánchez-Archidona AR, et al. Among authors: denom j. Mol Metab. 2021 Dec;54:101355. doi: 10.1016/j.molmet.2021.101355. Epub 2021 Oct 9. Mol Metab. 2021. PMID: 34634522 Free PMC article.
A surrogate of Roux-en-Y gastric bypass (the enterogastro anastomosis surgery) regulates multiple beta-cell pathways during resolution of diabetes in ob/ob mice.
Amouyal C, Castel J, Guay C, Lacombe A, Denom J, Migrenne-Li S, Rouault C, Marquet F, Georgiadou E, Stylianides T, Luquet S, Le Stunff H, Scharfmann R, Clément K, Rutter GA, Taboureau O, Magnan C, Regazzi R, Andreelli F. Amouyal C, et al. Among authors: denom j. EBioMedicine. 2020 Aug;58:102895. doi: 10.1016/j.ebiom.2020.102895. Epub 2020 Jul 30. EBioMedicine. 2020. PMID: 32739864 Free PMC article.
21 results