Mizushima N - Search Results

1

The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response.

Eguchi T, Sakurai M, Wang Y, Saito C, Yoshii G, Wileman T, Mizushima N, Kuwahara T, Iwatsubo T. Eguchi T, et al. Among authors: mizushima n. J Cell Biol. 2024 Mar 4;223(3):e202302067. doi: 10.1083/jcb.202302067. Epub 2024 Jan 16. J Cell Biol. 2024. PMID: 38227290 Free PMC article.

2

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.

Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, Mizushima N. Hara T, et al. Among authors: mizushima n. J Cell Biol. 2008 May 5;181(3):497-510. doi: 10.1083/jcb.200712064. Epub 2008 Apr 28. J Cell Biol. 2008. PMID: 18443221 Free PMC article.

3

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, Guan JL, Oshiro N, Mizushima N. Hosokawa N, et al. Among authors: mizushima n. Mol Biol Cell. 2009 Apr;20(7):1981-91. doi: 10.1091/mbc.e08-12-1248. Epub 2009 Feb 11. Mol Biol Cell. 2009. PMID: 19211835 Free PMC article.

4

p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding.

Itakura E, Mizushima N. Itakura E, et al. Among authors: mizushima n. J Cell Biol. 2011 Jan 10;192(1):17-27. doi: 10.1083/jcb.201009067. J Cell Biol. 2011. PMID: 21220506 Free PMC article.

5

The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17.

Jiang P, Nishimura T, Sakamaki Y, Itakura E, Hatta T, Natsume T, Mizushima N. Jiang P, et al. Among authors: mizushima n. Mol Biol Cell. 2014 Apr;25(8):1327-37. doi: 10.1091/mbc.E13-08-0447. Epub 2014 Feb 19. Mol Biol Cell. 2014. PMID: 24554770 Free PMC article.

6

Sugar modification inhibits autophagosome-lysosome fusion.

Mizushima N. Mizushima N. Nat Cell Biol. 2014 Dec;16(12):1132-3. doi: 10.1038/ncb3078. Nat Cell Biol. 2014. PMID: 25434465

7

Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide.

Wang C, Chen S, Yeo S, Karsli-Uzunbas G, White E, Mizushima N, Virgin HW, Guan JL. Wang C, et al. Among authors: mizushima n. J Cell Biol. 2016 Feb 29;212(5):545-60. doi: 10.1083/jcb.201507023. J Cell Biol. 2016. PMID: 26929451 Free PMC article.

8

Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17.

Matsui T, Jiang P, Nakano S, Sakamaki Y, Yamamoto H, Mizushima N. Matsui T, et al. Among authors: mizushima n. J Cell Biol. 2018 Aug 6;217(8):2633-2645. doi: 10.1083/jcb.201712058. Epub 2018 May 22. J Cell Biol. 2018. PMID: 29789439 Free PMC article.

9

Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation.

Morita K, Hama Y, Izume T, Tamura N, Ueno T, Yamashita Y, Sakamaki Y, Mimura K, Morishita H, Shihoya W, Nureki O, Mano H, Mizushima N. Morita K, et al. Among authors: mizushima n. J Cell Biol. 2018 Nov 5;217(11):3817-3828. doi: 10.1083/jcb.201804132. Epub 2018 Aug 9. J Cell Biol. 2018. PMID: 30093494 Free PMC article.

10

Diverse Cellular Roles of Autophagy.

Morishita H, Mizushima N. Morishita H, et al. Among authors: mizushima n. Annu Rev Cell Dev Biol. 2019 Oct 6;35:453-475. doi: 10.1146/annurev-cellbio-100818-125300. Epub 2019 Jul 5. Annu Rev Cell Dev Biol. 2019. PMID: 31283377 Review.

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