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Page 1
The art of designed coiled-coils for the regulation of mammalian cells.
Plaper T, Rihtar E, Železnik Ramuta T, Forstnerič V, Jazbec V, Ivanovski F, Benčina M, Jerala R. Plaper T, et al. Cell Chem Biol. 2024 Aug 15;31(8):1460-1472. doi: 10.1016/j.chembiol.2024.06.001. Epub 2024 Jul 5. Cell Chem Biol. 2024. PMID: 38971158 Free PMC article. Review.
Designed allosteric protein logic.
Plaper T, Merljak E, Fink T, Satler T, Ljubetič A, Lainšček D, Jazbec V, Benčina M, Stevanoska S, Džeroski S, Jerala R. Plaper T, et al. Cell Discov. 2024 Jan 16;10(1):8. doi: 10.1038/s41421-023-00635-y. Cell Discov. 2024. PMID: 38228615 Free PMC article.
Metal ion-regulated assembly of designed modular protein cages.
Aupič J, Lapenta F, Strmšek Ž, Merljak E, Plaper T, Jerala R. Aupič J, et al. Among authors: plaper t. Sci Adv. 2022 Jun 17;8(24):eabm8243. doi: 10.1126/sciadv.abm8243. Epub 2022 Jun 17. Sci Adv. 2022. PMID: 35714197 Free PMC article.
Disruption of disulfides within RBD of SARS-CoV-2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs.
Manček-Keber M, Hafner-Bratkovič I, Lainšček D, Benčina M, Govednik T, Orehek S, Plaper T, Jazbec V, Bergant V, Grass V, Pichlmair A, Jerala R. Manček-Keber M, et al. Among authors: plaper t. FASEB J. 2021 Jun;35(6):e21651. doi: 10.1096/fj.202100560R. FASEB J. 2021. PMID: 34004056 Free PMC article.
A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response.
Lainšček D, Fink T, Forstnerič V, Hafner-Bratkovič I, Orehek S, Strmšek Ž, Manček-Keber M, Pečan P, Esih H, Malenšek Š, Aupič J, Dekleva P, Plaper T, Vidmar S, Kadunc L, Benčina M, Omersa N, Anderluh G, Pojer F, Lau K, Hacker D, Correia BE, Peterhoff D, Wagner R, Bergant V, Herrmann A, Pichlmair A, Jerala R. Lainšček D, et al. Among authors: plaper t. Vaccines (Basel). 2021 Apr 27;9(5):431. doi: 10.3390/vaccines9050431. Vaccines (Basel). 2021. PMID: 33925446 Free PMC article.
Design of fast proteolysis-based signaling and logic circuits in mammalian cells.
Fink T, Lonzarić J, Praznik A, Plaper T, Merljak E, Leben K, Jerala N, Lebar T, Strmšek Ž, Lapenta F, Benčina M, Jerala R. Fink T, et al. Among authors: plaper t. Nat Chem Biol. 2019 Feb;15(2):115-122. doi: 10.1038/s41589-018-0181-6. Epub 2018 Dec 10. Nat Chem Biol. 2019. PMID: 30531965 Free PMC article.