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TAAR1 agonists improve glycemic control, reduce body weight and modulate neurocircuits governing energy balance and feeding.
Dedic N, Wang L, Hajos-Korcsok E, Hecksher-Sørensen J, Roostalu U, Vickers SP, Wu S, Anacker C, Synan C, Jones PG, Milanovic S, Hopkins SC, Bristow LJ, Koblan KS. Dedic N, et al. Among authors: hecksher sorensen j. Mol Metab. 2024 Feb;80:101883. doi: 10.1016/j.molmet.2024.101883. Epub 2024 Jan 16. Mol Metab. 2024. PMID: 38237896 Free PMC article.
GLP-1 and nicotine combination therapy engages hypothalamic and mesolimbic pathways to reverse obesity.
Falk S, Petersen J, Svendsen C, Romero-Leguizamón CR, Jørgensen SH, Krauth N, Ludwig MQ, Lundø K, Roostalu U, Skovbjerg G, Nielsen DAG, Ejdrup AL, Pers TH, Dmytriyeva O, Hecksher-Sørensen J, Gether U, Kohlmeier KA, Clemmensen C. Falk S, et al. Among authors: hecksher sorensen j. Cell Rep. 2023 May 30;42(5):112466. doi: 10.1016/j.celrep.2023.112466. Epub 2023 May 5. Cell Rep. 2023. PMID: 37148870 Free article.
Atlas of exercise-induced brain activation in mice.
Skovbjerg G, Fritzen AM, Svendsen CSA, Perens J, Skytte JL, Lund C, Lund J, Madsen MR, Roostalu U, Hecksher-Sørensen J, Clemmensen C. Skovbjerg G, et al. Among authors: hecksher sorensen j. Mol Metab. 2024 Apr;82:101907. doi: 10.1016/j.molmet.2024.101907. Epub 2024 Feb 28. Mol Metab. 2024. PMID: 38428817 Free PMC article.
Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis.
Bakker W, Imbernon M, Salinas CG, Moro Chao DH, Hassouna R, Morel C, Martin C, Leger C, Denis RGP, Castel J, Peter A, Heni M, Maetzler W, Nielsen HS, Duquenne M, Schwaninger M, Lundh S, Johan Hogendorf WF, Gangarossa G, Secher A, Hecksher-Sørensen J, Pedersen TÅ, Prevot V, Luquet S. Bakker W, et al. Among authors: hecksher sorensen j. Cell Rep. 2022 Nov 22;41(8):111698. doi: 10.1016/j.celrep.2022.111698. Cell Rep. 2022. PMID: 36417883 Free PMC article.
Whole-brain spatial transcriptional analysis at cellular resolution.
Kanatani S, Kreutzmann JC, Li Y, West Z, Larsen LL, Nikou DV, Eidhof I, Walton A, Zhang S, Rodríguez-Kirby LR, Skytte JL, Salinas CG, Takamatsu K, Li X, Tanaka DH, Kaczynska D, Fukumoto K, Karamzadeh R, Xiang Y, Uesaka N, Tanabe T, Adner M, Hartman J, Miyakawa A, Sundström E, Castelo-Branco G, Roostalu U, Hecksher-Sørensen J, Uhlén P. Kanatani S, et al. Among authors: hecksher sorensen j. Science. 2024 Nov 22;386(6724):907-915. doi: 10.1126/science.adn9947. Epub 2024 Nov 21. Science. 2024. PMID: 39571016
56 results