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Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia.
Gurbatri CR, Radford GA, Vrbanac L, Im J, Thomas EM, Coker C, Taylor SR, Jang Y, Sivan A, Rhee K, Saleh AA, Chien T, Zandkarimi F, Lia I, Lannagan TRM, Wang T, Wright JA, Kobayashi H, Ng JQ, Lawrence M, Sammour T, Thomas M, Lewis M, Papanicolas L, Perry J, Fitzsimmons T, Kaazan P, Lim A, Stavropoulos AM, Gouskos DA, Marker J, Ostroff C, Rogers G, Arpaia N, Worthley DL, Woods SL, Danino T. Gurbatri CR, et al. Among authors: chien t. Nat Commun. 2024 Jan 20;15(1):646. doi: 10.1038/s41467-024-44776-4. Nat Commun. 2024. PMID: 38245513 Free PMC article. Clinical Trial.
Colorectal cancer detection and treatment with engineered probiotics.
Gurbatri CR, Radford G, Vrbanac L, Coker C, Im JW, Taylor SR, Jang Y, Sivan A, Rhee K, Saleh AA, Chien T, Zandkarimi F, Lia I, Lannagan TR, Wang T, Wright JA, Thomas E, Kobayashi H, Ng JQ, Lawrence M, Sammour T, Thomas M, Lewis M, Papanicolas L, Perry J, Fitzsimmons T, Kaazan P, Lim A, Marker J, Ostroff C, Rogers G, Arpaia N, Worthley DL, Woods SL, Danino T. Gurbatri CR, et al. Among authors: chien t. bioRxiv [Preprint]. 2023 Apr 5:2023.04.03.535370. doi: 10.1101/2023.04.03.535370. bioRxiv. 2023. PMID: 37066243 Free PMC article. Preprint.
Enhancing the tropism of bacteria via genetically programmed biosensors.
Chien T, Harimoto T, Kepecs B, Gray K, Coker C, Hou N, Pu K, Azad T, Nolasco A, Pavlicova M, Danino T. Chien T, et al. Nat Biomed Eng. 2022 Jan;6(1):94-104. doi: 10.1038/s41551-021-00772-3. Epub 2021 Jul 29. Nat Biomed Eng. 2022. PMID: 34326488 Free PMC article.
495 results