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A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity.
Patel AG, Ashenberg O, Collins NB, Segerstolpe Å, Jiang S, Slyper M, Huang X, Caraccio C, Jin H, Sheppard H, Xu K, Chang TC, Orr BA, Shirinifard A, Chapple RH, Shen A, Clay MR, Tatevossian RG, Reilly C, Patel J, Lupo M, Cline C, Dionne D, Porter CBM, Waldman J, Bai Y, Zhu B, Barrera I, Murray E, Vigneau S, Napolitano S, Wakiro I, Wu J, Grimaldi G, Dellostritto L, Helvie K, Rotem A, Lako A, Cullen N, Pfaff KL, Karlström Å, Jané-Valbuena J, Todres E, Thorner A, Geeleher P, Rodig SJ, Zhou X, Stewart E, Johnson BE, Wu G, Chen F, Yu J, Goltsev Y, Nolan GP, Rozenblatt-Rosen O, Regev A, Dyer MA. Patel AG, et al. Among authors: wu g, wu j. bioRxiv [Preprint]. 2024 Jan 16:2024.01.07.574538. doi: 10.1101/2024.01.07.574538. bioRxiv. 2024. PMID: 38260392 Free PMC article. Preprint.
Retinoblastoma from human stem cell-derived retinal organoids.
Norrie JL, Nityanandam A, Lai K, Chen X, Wilson M, Stewart E, Griffiths L, Jin H, Wu G, Orr B, Tran Q, Allen S, Reilly C, Zhou X, Zhang J, Newman K, Johnson D, Brennan R, Dyer MA. Norrie JL, et al. Among authors: wu g. Nat Commun. 2021 Jul 27;12(1):4535. doi: 10.1038/s41467-021-24781-7. Nat Commun. 2021. PMID: 34315877 Free PMC article.
Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor.
Jablonowski C, Quarni W, Singh S, Tan H, Bostanthirige DH, Jin H, Fang J, Chang TC, Finkelstein D, Cho JH, Hu D, Pagala V, Sakurada SM, Pruett-Miller SM, Wang R, Murphy A, Freeman K, Peng J, Davidoff AM, Wu G, Yang J. Jablonowski C, et al. Among authors: wu g. bioRxiv [Preprint]. 2023 Nov 20:2023.06.26.546606. doi: 10.1101/2023.06.26.546606. bioRxiv. 2023. Update in: Elife. 2024 Mar 15;12:RP90993. doi: 10.7554/eLife.90993 PMID: 37425900 Free PMC article. Updated. Preprint.
Genomic profiling of circulating tumor DNA for childhood cancers.
Lei S, Jia S, Takalkar S, Chang TC, Ma X, Szlachta K, Xu K, Cheng Z, Hui Y, Koo SC, Mead PE, Gao Q, Kumar P, Bailey CP, Sunny J, Pappo AS, Federico SM, Robinson GW, Gajjar A, Rubnitz JE, Jeha S, Pui CH, Inaba H, Wu G, Klco JM, Tatevossian RG, Mullighan CG. Lei S, et al. Among authors: wu g. Leukemia. 2024 Nov 10. doi: 10.1038/s41375-024-02461-x. Online ahead of print. Leukemia. 2024. PMID: 39523434
Comprehensive genomic analysis reveals molecular heterogeneity in pediatric ALK-positive anaplastic large cell lymphoma.
Shaw TI, Pounds S, Cao X, Ma J, Palacios G, Mason J, Perkins S, Wu G, Fan Y, Wang J, Zhou X, Obermayer A, Kinney MC, Kraveka J, Gross T, Sandlund J, Zhang J, Mullighan C, Lim MS, Leventaki V. Shaw TI, et al. Among authors: wu g. Leukemia. 2025 Jan;39(1):199-210. doi: 10.1038/s41375-024-02468-4. Epub 2024 Nov 26. Leukemia. 2025. PMID: 39592809
Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource.
Smith KS, Xu K, Mercer KS, Boop F, Klimo P, DeCupyere M, Grenet J, Robinson S, Dunphy P, Baker SJ, Ellison DW, Merchant TE, Upadayaya SA, Gajjar A, Wu G, Orr BA, Robinson GW, Northcott PA, Roussel MF. Smith KS, et al. Among authors: wu g. Acta Neuropathol. 2020 Aug;140(2):209-225. doi: 10.1007/s00401-020-02171-5. Epub 2020 Jun 10. Acta Neuropathol. 2020. PMID: 32519082 Free PMC article.
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