Pitson SM - Search Results

1

Mitochondrial translocation of TFEB regulates complex I and inflammation.

Calabrese C, Nolte H, Pitman MR, Ganesan R, Lampe P, Laboy R, Ripa R, Fischer J, Polara R, Panda SK, Chipurupalli S, Gutierrez S, Thomas D, Pitson SM, Antebi A, Robinson N. Calabrese C, et al. Among authors: pitson sm. EMBO Rep. 2024 Feb;25(2):704-724. doi: 10.1038/s44319-024-00058-0. Epub 2024 Jan 23. EMBO Rep. 2024. PMID: 38263327 Free PMC article.

2

Inhibitors of the sphingosine kinase pathway as potential therapeutics.

Pitman MR, Pitson SM. Pitman MR, et al. Among authors: pitson sm. Curr Cancer Drug Targets. 2010 Jun;10(4):354-67. doi: 10.2174/156800910791208599. Curr Cancer Drug Targets. 2010. PMID: 20370685 Review.

3

A critical role for the protein phosphatase 2A B'α regulatory subunit in dephosphorylation of sphingosine kinase 1.

Pitman MR, Barr RK, Gliddon BL, Magarey AM, Moretti PA, Pitson SM. Pitman MR, et al. Among authors: pitson sm. Int J Biochem Cell Biol. 2011 Mar;43(3):342-7. doi: 10.1016/j.biocel.2010.11.001. Epub 2010 Nov 11. Int J Biochem Cell Biol. 2011. PMID: 21075214

4

Isoform-selective assays for sphingosine kinase activity.

Pitman MR, Pham DH, Pitson SM. Pitman MR, et al. Among authors: pitson sm. Methods Mol Biol. 2012;874:21-31. doi: 10.1007/978-1-61779-800-9_2. Methods Mol Biol. 2012. PMID: 22528436

5

Molecular targets of FTY720 (fingolimod).

Pitman MR, Woodcock JM, Lopez AF, Pitson SM. Pitman MR, et al. Among authors: pitson sm. Curr Mol Med. 2012 Dec;12(10):1207-19. doi: 10.2174/156652412803833599. Curr Mol Med. 2012. PMID: 22834825 Review.

6

A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties.

Pitman MR, Powell JA, Coolen C, Moretti PA, Zebol JR, Pham DH, Finnie JW, Don AS, Ebert LM, Bonder CS, Gliddon BL, Pitson SM. Pitman MR, et al. Among authors: pitson sm. Oncotarget. 2015 Mar 30;6(9):7065-83. doi: 10.18632/oncotarget.3178. Oncotarget. 2015. PMID: 25788259 Free PMC article.

7

From Sphingosine Kinase to Dihydroceramide Desaturase: A Structure-Activity Relationship (SAR) Study of the Enzyme Inhibitory and Anticancer Activity of 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol (SKI-II).

Aurelio L, Scullino CV, Pitman MR, Sexton A, Oliver V, Davies L, Rebello RJ, Furic L, Creek DJ, Pitson SM, Flynn BL. Aurelio L, et al. Among authors: pitson sm. J Med Chem. 2016 Feb 11;59(3):965-84. doi: 10.1021/acs.jmedchem.5b01439. Epub 2016 Feb 3. J Med Chem. 2016. PMID: 26780304

8

Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells.

McNaughton M, Pitman M, Pitson SM, Pyne NJ, Pyne S. McNaughton M, et al. Among authors: pitson sm. Oncotarget. 2016 Mar 29;7(13):16663-75. doi: 10.18632/oncotarget.7693. Oncotarget. 2016. PMID: 26934645 Free PMC article.

9

Topical Application of Fingolimod Perturbs Cutaneous Inflammation.

Sun WY, Dimasi DP, Pitman MR, Zhuang Y, Heddle R, Pitson SM, Grimbaldeston MA, Bonder CS. Sun WY, et al. Among authors: pitson sm. J Immunol. 2016 May 1;196(9):3854-64. doi: 10.4049/jimmunol.1501510. Epub 2016 Mar 21. J Immunol. 2016. PMID: 27001955

10

Recent advances in the development of sphingosine kinase inhibitors.

Pitman MR, Costabile M, Pitson SM. Pitman MR, et al. Among authors: pitson sm. Cell Signal. 2016 Sep;28(9):1349-1363. doi: 10.1016/j.cellsig.2016.06.007. Epub 2016 Jun 11. Cell Signal. 2016. PMID: 27297359 Review.

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