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H2Bub1 loss is an early contributor to clear cell ovarian cancer progression.
Ferrari AJ, Rawat P, Rendulich HS, Annapragada AV, Kinose Y, Zhang X, Devins K, Budina A, Scharpf RB, Mitchell MA, Tanyi JL, Morgan MA, Schwartz LE, Soong TR, Velculescu VE, Drapkin R. Ferrari AJ, et al. Among authors: drapkin r. JCI Insight. 2023 Jun 22;8(12):e164995. doi: 10.1172/jci.insight.164995. JCI Insight. 2023. PMID: 37345659 Free PMC article.
Targeting NaPi2b in ovarian cancer.
Banerjee S, Drapkin R, Richardson DL, Birrer M. Banerjee S, et al. Among authors: drapkin r. Cancer Treat Rev. 2023 Jan;112:102489. doi: 10.1016/j.ctrv.2022.102489. Epub 2022 Nov 14. Cancer Treat Rev. 2023. PMID: 36446254 Free article. Review.
Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis.
Zhou W, Liu H, Yuan Z, Zundell J, Towers M, Lin J, Lombardi S, Nie H, Murphy B, Yang T, Wang C, Liao L, Goldman AR, Kannan T, Kossenkov AV, Drapkin R, Montaner LJ, Claiborne DT, Zhang N, Wu S, Zhang R. Zhou W, et al. Among authors: drapkin r. Cancer Cell. 2023 Apr 10;41(4):740-756.e10. doi: 10.1016/j.ccell.2023.03.002. Epub 2023 Mar 23. Cancer Cell. 2023. PMID: 36963401 Free PMC article.
ZNFX1 functions as a master regulator of epigenetically induced pathogen mimicry and inflammasome signaling in cancer.
Stojanovic L, Abbotts R, Tripathi K, Coon CM, Rajendran S, Abbasi Farid E, Hostetter G, Guarnieri JW, Wallace DC, Liu S, Wan J, Calendo G, Marker R, Gohari Z, Inayatullah MMA, Tiwari VK, Kader T, Santagata S, Drapkin R, Kommoss S, Pfisterer J, Konecny GE, Coopergard R, Issa JJ, Winterhoff BJN, Topper MJ, Sandusky GE, Miller KD, Baylin SB, Nephew KP, Rassool FV. Stojanovic L, et al. Among authors: drapkin r. Cancer Res. 2025 Jan 13. doi: 10.1158/0008-5472.CAN-24-1286. Online ahead of print. Cancer Res. 2025. PMID: 39804147
Cycling Molecular Assemblies for Selective Cancer Cell Golgi Disruption.
Tan W, Zhang Q, Liu Z, Qiu K, Mahajan D, Gerton T, Copperman N, Xia C, Lin C, Lau W, Lee M, Ashton-Rickardt I, Hong P, Dinulescu D, Hsieh JT, Loeb D, Drapkin R, Diao J, Lu L, Xu B. Tan W, et al. Among authors: drapkin r. bioRxiv [Preprint]. 2025 Jan 5:2025.01.05.631374. doi: 10.1101/2025.01.05.631374. bioRxiv. 2025. PMID: 39803570 Free PMC article. Preprint.
Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma.
Kader T, Lin JR, Hug CB, Coy S, Chen YA, de Bruijn I, Shih N, Jung E, Pelletier RJ, Lopez Leon M, Mingo G, Omran DK, Lee JS, Yapp C, Satravada BA, Kundra R, Xu Y, Chan S, Tefft JB, Muhlich JL, Kim SH, Gysler SM, Agudo J, Heath JR, Schultz N, Drescher CW, Sorger PK, Drapkin R, Santagata S. Kader T, et al. Among authors: drapkin r. Cancer Discov. 2024 Dec 20. doi: 10.1158/2159-8290.CD-24-1366. Online ahead of print. Cancer Discov. 2024. PMID: 39704522
267 results