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Page 1
Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas.
Hariharan S, Whitfield BT, Pirozzi CJ, Waitkus MS, Brown MC, Bowie ML, Irvin DM, Roso K, Fuller R, Hostettler J, Dharmaiah S, Gibson EA, Briley A, Mangoli A, Fraley C, Shobande M, Stevenson K, Zhang G, Malgulwar PB, Roberts H, Roskoski M, Spasojevic I, Keir ST, He Y, Castro MG, Huse JT, Ashley DM. Hariharan S, et al. Among authors: huse jt. Nat Commun. 2024 Jan 25;15(1):730. doi: 10.1038/s41467-024-44932-w. Nat Commun. 2024. PMID: 38272925 Free PMC article.
Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma.
Malgulwar PB, Danussi C, Dharmaiah S, Johnson WE, Rao A, Huse JT. Malgulwar PB, et al. Among authors: huse jt. bioRxiv [Preprint]. 2023 Jan 10:2023.01.09.523324. doi: 10.1101/2023.01.09.523324. bioRxiv. 2023. Update in: Neuro Oncol. 2024 Jan 5;26(1):55-67. doi: 10.1093/neuonc/noad155 PMID: 36711727 Free PMC article. Updated. Preprint.
Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas.
Hariharan S, Whitfield BT, Pirozzi CJ, Waitkus MS, Brown MC, Bowie ML, Irvin DM, Roso K, Fuller R, Hostettler J, Dharmaiah S, Gibson EA, Briley A, Mangoli A, Fraley C, Shobande M, Stevenson K, Zhang G, Malgulwar PB, Roberts H, Roskoski M, Spasojevic I, Keir ST, He Y, Castro MG, Huse JT, Ashley DM. Hariharan S, et al. Among authors: huse jt. bioRxiv [Preprint]. 2023 Apr 21:2023.04.20.537594. doi: 10.1101/2023.04.20.537594. bioRxiv. 2023. Update in: Nat Commun. 2024 Jan 25;15(1):730. doi: 10.1038/s41467-024-44932-w PMID: 37131619 Free PMC article. Updated. Preprint.
A brave new framework for glioma drug development.
Hotchkiss KM, Karschnia P, Schreck KC, Geurts M, Cloughesy TF, Huse J, Duke ES, Lathia J, Ashley DM, Nduom EK, Long G, Singh K, Chalmers A, Ahluwalia MS, Heimberger A, Bagley S, Todo T, Verhaak R, Kelly PD, Hervey-Jumper S, de Groot J, Patel A, Fecci P, Parney I, Wykes V, Watts C, Burns TC, Sanai N, Preusser M, Tonn JC, Drummond KJ, Platten M, Das S, Tanner K, Vogelbaum MA, Weller M, Whittle JR, Berger MS, Khasraw M. Hotchkiss KM, et al. Lancet Oncol. 2024 Oct;25(10):e512-e519. doi: 10.1016/S1470-2045(24)00190-6. Lancet Oncol. 2024. PMID: 39362262 Review.
The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen.
Malta TM, Sabedot TS, Morosini NS, Datta I, Garofano L, Vallentgoed W, Varn FS, Aldape K, D'Angelo F, Bakas S, Barnholtz-Sloan JS, Gan HK, Hasanain M, Hau AC, Johnson KC, Cazacu S, deCarvalho AC, Khasraw M, Kocakavuk E, Kouwenhoven MCM, Migliozzi S, Niclou SP, Niers JM, Ormond DR, Paek SH, Reifenberger G, Sillevis Smitt PA, Smits M, Stead LF, van den Bent MJ, Van Meir EG, Walenkamp A, Weiss T, Weller M, Westerman BA, Ylstra B, Wesseling P, Lasorella A, French PJ, Poisson LM; Consortium The GLASS; Verhaak RGW, Iavarone A, Noushmehr H. Malta TM, et al. Cancer Res. 2024 Mar 4;84(5):741-756. doi: 10.1158/0008-5472.CAN-23-2093. Cancer Res. 2024. PMID: 38117484 Free PMC article.
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
Cancer Genome Atlas Research Network; Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O'Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla … See abstract for full author list ➔ Cancer Genome Atlas Research Network, et al. Among authors: huse jt. N Engl J Med. 2015 Jun 25;372(26):2481-98. doi: 10.1056/NEJMoa1402121. Epub 2015 Jun 10. N Engl J Med. 2015. PMID: 26061751 Free PMC article.
Molecular Testing for the World Health Organization Classification of Central Nervous System Tumors: A Review.
Horbinski C, Solomon DA, Lukas RV, Packer RJ, Brastianos P, Wen PY, Snuderl M, Berger MS, Chang S, Fouladi M, Phillips JJ, Nabors B, Brat DJ, Huse JT, Aldape K, Sarkaria JN, Holdhoff M, Burns TC, Peters KB, Mellinghoff IK, Arons D, Galanis E. Horbinski C, et al. Among authors: huse jt. JAMA Oncol. 2024 Dec 26. doi: 10.1001/jamaoncol.2024.5506. Online ahead of print. JAMA Oncol. 2024. PMID: 39724142
Astrocyte-induced Cdk5 expedites breast cancer brain metastasis by suppressing MHC-I expression to evade immune recognition.
Yuzhalin AE, Lowery FJ, Saito Y, Yuan X, Yao J, Duan Y, Ding J, Acharya S, Zhang C, Fajardo A, Chen HN, Wei Y, Sun Y, Zhang L, Xiao Y, Li P, Lorenzi PL, Huse JT, Fan H, Zhao Z, Hung MC, Yu D. Yuzhalin AE, et al. Among authors: huse jt. Nat Cell Biol. 2024 Oct;26(10):1773-1789. doi: 10.1038/s41556-024-01509-5. Epub 2024 Sep 20. Nat Cell Biol. 2024. PMID: 39304713
Fibrotic response to anti-CSF-1R therapy potentiates glioblastoma recurrence.
Watson SS, Zomer A, Fournier N, Lourenco J, Quadroni M, Chryplewicz A, Nassiri S, Aubel P, Avanthay S, Croci D, Abels E, Broekman MLD, Hanahan D, Huse JT, Daniel RT, Hegi ME, Homicsko K, Cossu G, Hottinger AF, Joyce JA. Watson SS, et al. Among authors: huse jt. Cancer Cell. 2024 Sep 9;42(9):1507-1527.e11. doi: 10.1016/j.ccell.2024.08.012. Cancer Cell. 2024. PMID: 39255775 Free article.
167 results