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Page 1
Activation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells.
Gurrea-Rubio M, Wu Q, Amin MA, Tsou PS, Campbell PL, Amarista CI, Ikari Y, Brodie WD, Mattichak MN, Muraoka S, Randon PM, Lind ME, Ruth JH, Mao-Draayer Y, Ding S, Shen X, Cooney LA, Lin F, Fox DA. Gurrea-Rubio M, et al. Among authors: brodie wd. Cancer Immunol Immunother. 2024 Jan 27;73(2):34. doi: 10.1007/s00262-023-03578-1. Cancer Immunol Immunother. 2024. PMID: 38280067 Free PMC article.
Inhibition of bromodomain extraterminal histone readers alleviates skin fibrosis in experimental models of scleroderma.
Vichaikul S, Gurrea-Rubio M, Amin MA, Campbell PL, Wu Q, Mattichak MN, Brodie WD, Palisoc PJ, Ali M, Muraoka S, Ruth JH, Model EN, Rohraff DM, Hervoso JL, Mao-Draayer Y, Fox DA, Khanna D, Sawalha AH, Tsou PS. Vichaikul S, et al. Among authors: brodie wd. JCI Insight. 2022 May 9;7(9):e150871. doi: 10.1172/jci.insight.150871. JCI Insight. 2022. PMID: 35349485 Free PMC article.
Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1.
Tsou PS, Lu C, Gurrea-Rubio M, Muraoka S, Campbell PL, Wu Q, Model EN, Lind ME, Vichaikul S, Mattichak MN, Brodie WD, Hervoso JL, Ory S, Amarista CI, Pervez R, Junginger L, Ali M, Hodish G, O'Mara MM, Ruth JH, Robida AM, Alt AJ, Zhang C, Urquhart AG, Lawton JN, Chung KC, Maerz T, Saunders TL, Groppi VE, Fox DA, Amin MA. Tsou PS, et al. Among authors: brodie wd. J Clin Invest. 2022 Jun 1;132(11):e151827. doi: 10.1172/JCI151827. J Clin Invest. 2022. PMID: 35439173 Free PMC article.
Activation of Cytotoxic Lymphocytes Through CD6 Enhances Killing of Cancer Cells.
Gurrea-Rubio M, Wu Q, Amin MA, Tsou PS, Campbell PL, Amarista CE, Ikari Y, Brodie WD, Mattichak MN, Muraoka S, Randon PM, Lind ME, Ruth JH, Mao-Draayer Y, Ding S, Shen X, Cooney LA, Lin F, Fox DA. Gurrea-Rubio M, et al. Among authors: brodie wd. Res Sq [Preprint]. 2023 Oct 9:rs.3.rs-3405677. doi: 10.21203/rs.3.rs-3405677/v1. Res Sq. 2023. Update in: Cancer Immunol Immunother. 2024 Jan 27;73(2):34. doi: 10.1007/s00262-023-03578-1 PMID: 37886483 Free PMC article. Updated. Preprint.
Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa.
van Straalen KR, Ma F, Tsou PS, Plazyo O, Gharaee-Kermani M, Calbet M, Xing X, Sarkar MK, Uppala R, Harms PW, Wasikowski R, Nahlawi L, Nakamura M, Eshaq M, Wang C, Dobry C, Kozlow JH, Cherry-Bukowiec J, Brodie WD, Wolk K, Uluçkan Ö, Mattichak MN, Pellegrini M, Modlin RL, Maverakis E, Sabat R, Kahlenberg JM, Billi AC, Tsoi LC, Gudjonsson JE. van Straalen KR, et al. Among authors: brodie wd. J Clin Invest. 2024 Feb 1;134(3):e169225. doi: 10.1172/JCI169225. J Clin Invest. 2024. PMID: 38051587 Free PMC article.
Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis.
Ma F, Tsou PS, Gharaee-Kermani M, Plazyo O, Xing X, Kirma J, Wasikowski R, Hile GA, Harms PW, Jiang Y, Xing E, Nakamura M, Ochocki D, Brodie WD, Pillai S, Maverakis E, Pellegrini M, Modlin RL, Varga J, Tsoi LC, Lafyatis R, Kahlenberg JM, Billi AC, Khanna D, Gudjonsson JE. Ma F, et al. Among authors: brodie wd. Nat Commun. 2024 Jan 3;15(1):210. doi: 10.1038/s41467-023-44645-6. Nat Commun. 2024. PMID: 38172207 Free PMC article.
Targeting CD13/Aminopeptidase N as a Novel Therapeutic Approach for Scleroderma Fibrosis.
Muraoka S, Brodie WD, Mattichak MN, Gurrea-Rubio M, Ikari Y, Foster C, Amin MA, Khanna N, Amin H, Campbell PL, Vichaikul S, Model EN, Omara MM, Petrovski S, Kozicki K, Amarista C, Webber A, Ali M, Palisoc PJ, Hervoso J, Ruth JH, Tsoi LC, Varga J, Gudjonsson JE, Khanna D, Fox DA, Tsou PS. Muraoka S, et al. Among authors: brodie wd. Arthritis Rheumatol. 2025 Jan;77(1):80-91. doi: 10.1002/art.42973. Epub 2024 Sep 18. Arthritis Rheumatol. 2025. PMID: 39175116 Free PMC article.