Lv J - Search Results

1

AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial.

Lv J, Wang H, Cheng X, Chen Y, Wang D, Zhang L, Cao Q, Tang H, Hu S, Gao K, Xun M, Wang J, Wang Z, Zhu B, Cui C, Gao Z, Guo L, Yu S, Jiang L, Yin Y, Zhang J, Chen B, Wang W, Chai R, Chen ZY, Li H, Shu Y. Lv J, et al. Lancet. 2024 May 25;403(10441):2317-2325. doi: 10.1016/S0140-6736(23)02874-X. Epub 2024 Jan 24. Lancet. 2024. PMID: 38280389 Clinical Trial.

2

Deletion of Kcnj16 in Mice Does Not Alter Auditory Function.

Lv J, Fu X, Li Y, Hong G, Li P, Lin J, Xun Y, Fang L, Weng W, Yue R, Li GL, Guan B, Li H, Huang Y, Chai R. Lv J, et al. Front Cell Dev Biol. 2021 Feb 22;9:630361. doi: 10.3389/fcell.2021.630361. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33693002 Free PMC article.

3

A humanized murine model, demonstrating dominant progressive hearing loss caused by a novel KCNQ4 mutation (p.G228D) from a large Chinese family.

Cui C, Zhang L, Qian F, Chen Y, Huang B, Wang F, Wang D, Lv J, Wang X, Yan Z, Guo L, Li GL, Shu Y, Liu D, Li H. Cui C, et al. Among authors: lv j. Clin Genet. 2022 Aug;102(2):149-154. doi: 10.1111/cge.14164. Epub 2022 May 28. Clin Genet. 2022. PMID: 35599357

4

Precise detection of CRISPR-Cas9 editing in hair cells in the treatment of autosomal dominant hearing loss.

Cui C, Wang D, Huang B, Wang F, Chen Y, Lv J, Zhang L, Han L, Liu D, Chen ZY, Li GL, Li H, Shu Y. Cui C, et al. Among authors: lv j. Mol Ther Nucleic Acids. 2022 Jul 20;29:400-412. doi: 10.1016/j.omtn.2022.07.016. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 36035752 Free PMC article.

5

Hearing of Otof-deficient mice restored by trans-splicing of N- and C-terminal otoferlin.

Tang H, Wang H, Wang S, Hu SW, Lv J, Xun M, Gao K, Wang F, Chen Y, Wang D, Wang W, Li H, Shu Y. Tang H, et al. Among authors: lv j. Hum Genet. 2023 Feb;142(2):289-304. doi: 10.1007/s00439-022-02504-2. Epub 2022 Nov 16. Hum Genet. 2023. PMID: 36383253

6

The pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice.

Li Q, Cui C, Liao R, Yin X, Wang D, Cheng Y, Huang B, Wang L, Yan M, Zhou J, Zhao J, Tang W, Wang Y, Wang X, Lv J, Li J, Li H, Shu Y. Li Q, et al. Among authors: lv j. Cell Mol Life Sci. 2023 May 13;80(6):148. doi: 10.1007/s00018-023-04794-9. Cell Mol Life Sci. 2023. PMID: 37178259 Free PMC article.

7

Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and nonhuman primates.

Zhang L, Wang H, Xun M, Tang H, Wang J, Lv J, Zhu B, Chen Y, Wang D, Hu S, Gao Z, Liu J, Chen ZY, Chen B, Li H, Shu Y. Zhang L, et al. Among authors: lv j. Mol Ther Methods Clin Dev. 2023 Nov 10;31:101154. doi: 10.1016/j.omtm.2023.101154. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 38027066 Free PMC article.

8

[Study on gene therapy for DPOAE and ABR threshold changes in adult Otof-/- mice].

Wang Z, Cao Q, Hu S, Fan X, Lv J, Wang H, Wang W, Li H, Shu Y. Wang Z, et al. Among authors: lv j. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Jan;38(1):49-56. doi: 10.13201/j.issn.2096-7993.2024.01.008. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024. PMID: 38297849 Free PMC article. Chinese.

9

Hair cell-specific Myo15 promoter-mediated gene therapy rescues hearing in DFNB9 mouse model.

Wang H, Xun M, Tang H, Zhao J, Hu S, Zhang L, Lv J, Wang D, Chen Y, Liu J, Li GL, Wang W, Shu Y, Li H. Wang H, et al. Among authors: lv j. Mol Ther Nucleic Acids. 2024 Feb 2;35(1):102135. doi: 10.1016/j.omtn.2024.102135. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2024. PMID: 38404504 Free PMC article.

10

A Novel Delivery Approach of Clinical Inner Ear Gene Therapy.

Zhang LL, Wang J, Gao ZW, Lv J, Jiang LY, Cui C, Wang ZJ, Wang DQ, Chen YX, Fan XT, Ye C, Wang H, Chen B, Wang WQ, Li HW, Shu YL. Zhang LL, et al. Among authors: lv j. Otol Neurotol. 2025 Jan 1;46(1):31-38. doi: 10.1097/MAO.0000000000004366. Epub 2024 Nov 6. Otol Neurotol. 2025. PMID: 39511736

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