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Page 1
Metabolomic and lipidomic pathways in aneurysmal subarachnoid hemorrhage.
Yang BSK, Blackburn SL, Lorenzi PL, Choi HA, Gusdon AM. Yang BSK, et al. Among authors: lorenzi pl. Neurotherapeutics. 2024 Dec 19:e00504. doi: 10.1016/j.neurot.2024.e00504. Online ahead of print. Neurotherapeutics. 2024. PMID: 39701893 Free article. Review.
WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer.
Citron F, Ho IL, Balestrieri C, Liu Z, Yen EN, Cecchetto L, Perelli L, Zhang L, Castillo Montanez LA, Blazanin N, Dyke CA, Shah R, Attanasio S, Srinivasan S, Chen KC, Chen Z, Scognamiglio I, Pham N, Khan H, Jiang S, Pan J, Vanderkruk B, Leung C, Mattohti M, Rai K, Chu Y, Wang L, Gao S, Deem AK, Carugo A, Wang H, Yao W, Tonon G, Xiong Y, Lorenzi PL, Bonini C, Zal A, Hoffman B, Giuliani V, Heffernan T, Jeter CR, Lissanu Y, Genovese G, Di Pilato M, Viale A, Draetta GF. Citron F, et al. Among authors: lorenzi pl. bioRxiv [Preprint]. 2025 Jan 2:2024.10.21.619543. doi: 10.1101/2024.10.21.619543. bioRxiv. 2025. PMID: 39484624 Free PMC article. Preprint.
Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma.
Chattopadhyay C, Roszik J, Bhattacharya R, Alauddin M, Mahmud I, Yadugiri S, Ali MM, Khan FS, Prabhu VV, Lorenzi PL, Wei B, Burton E, Morey RR, Lazcano R, Davies MA, Patel SP, Grimm EA. Chattopadhyay C, et al. Among authors: lorenzi pl. Br J Cancer. 2024 Dec;131(11):1846-1857. doi: 10.1038/s41416-024-02866-6. Epub 2024 Oct 11. Br J Cancer. 2024. PMID: 39394450 Free PMC article.
Therapeutic modulation of ROCK overcomes metabolic adaptation of cancer cells to OXPHOS inhibition and drives synergistic anti-tumor activity.
Blazanin N, Liang X, Mahmud I, Kim E, Martinez S, Tan L, Chan W, Anvar NE, Ha MJ, Qudratullah M, Minelli R, Peoples M, Lorenzi P, Hart T, Lissanu Y. Blazanin N, et al. Among authors: lorenzi p. bioRxiv [Preprint]. 2024 Sep 20:2024.09.16.613317. doi: 10.1101/2024.09.16.613317. bioRxiv. 2024. PMID: 39345502 Free PMC article. Preprint.
Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis.
Das S, Finney AC, Anand SK, Rohilla S, Liu Y, Pandey N, Ghrayeb A, Kumar D, Nunez K, Liu Z, Arias F, Zhao Y, Pearson-Gallion BH, McKinney MP, Richard KSE, Gomez-Vidal JA, Abdullah CS, Cockerham ED, Eniafe J, Yurochko AD, Magdy T, Pattillo CB, Kevil CG, Razani B, Bhuiyan MS, Seeley EH, Galliano GE, Wei B, Tan L, Mahmud I, Surakka I, Garcia-Barrio MT, Lorenzi PL, Gottlieb E, Salido E, Zhang J, Orr AW, Liu W, Diaz-Gavilan M, Chen YE, Dhanesha N, Thevenot PT, Cohen AJ, Yurdagul A Jr, Rom O. Das S, et al. Among authors: lorenzi pl. Nat Metab. 2024 Oct;6(10):1939-1962. doi: 10.1038/s42255-024-01134-4. Epub 2024 Sep 27. Nat Metab. 2024. PMID: 39333384 Free PMC article.
Astrocyte-induced Cdk5 expedites breast cancer brain metastasis by suppressing MHC-I expression to evade immune recognition.
Yuzhalin AE, Lowery FJ, Saito Y, Yuan X, Yao J, Duan Y, Ding J, Acharya S, Zhang C, Fajardo A, Chen HN, Wei Y, Sun Y, Zhang L, Xiao Y, Li P, Lorenzi PL, Huse JT, Fan H, Zhao Z, Hung MC, Yu D. Yuzhalin AE, et al. Among authors: lorenzi pl. Nat Cell Biol. 2024 Oct;26(10):1773-1789. doi: 10.1038/s41556-024-01509-5. Epub 2024 Sep 20. Nat Cell Biol. 2024. PMID: 39304713
Protection against fibrosis by a bacterial consortium in metabolic dysfunction-associated steatohepatitis and the role of amino acid metabolism.
Kwan SY, Gonzales KA, Jamal MA, Stevenson HL, Tan L, Lorenzi PL, Futreal PA, Hawk ET, McCormick JB, Fisher-Hoch SP, Jenq RR, Beretta L. Kwan SY, et al. Among authors: lorenzi pl. Gut Microbes. 2024 Jan-Dec;16(1):2399260. doi: 10.1080/19490976.2024.2399260. Epub 2024 Sep 6. Gut Microbes. 2024. PMID: 39239875 Free PMC article.
Bacteroides ovatus alleviates dysbiotic microbiota-induced graft-versus-host disease.
Hayase E, Hayase T, Mukherjee A, Stinson SC, Jamal MA, Ortega MR, Sanchez CA, Ahmed SS, Karmouch JL, Chang CC, Flores II, McDaniel LK, Brown AN, El-Himri RK, Chapa VA, Tan L, Tran BQ, Xiao Y, Fan C, Pham D, Halsey TM, Jin Y, Tsai WB, Prasad R, Glover IK, Enkhbayar A, Mohammed A, Schmiester M, King KY, Britton RA, Reddy P, Wong MC, Ajami NJ, Wargo JA, Shelburne S, Okhuysen PC, Liu C, Fowler SW, Conner ME, Katsamakis Z, Smith N, Burgos da Silva M, Ponce DM, Peled JU, van den Brink MRM, Peterson CB, Rondon G, Molldrem JJ, Champlin RE, Shpall EJ, Lorenzi PL, Mehta RS, Martens EC, Alousi AM, Jenq RR. Hayase E, et al. Among authors: lorenzi pl. Cell Host Microbe. 2024 Sep 11;32(9):1621-1636.e6. doi: 10.1016/j.chom.2024.08.004. Epub 2024 Aug 29. Cell Host Microbe. 2024. PMID: 39214085
213 results