Phizicky EM - Search Results

1

A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay.

De Zoysa T, Hauke AC, Iyer NR, Marcus E, Ostrowski SM, Stegemann F, Ermolenko DN, Fay JC, Phizicky EM. De Zoysa T, et al. Among authors: phizicky em. PLoS Genet. 2024 Jan 31;20(1):e1011146. doi: 10.1371/journal.pgen.1011146. eCollection 2024 Jan. PLoS Genet. 2024. PMID: 38295128 Free PMC article.

2

Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequences.

De Zoysa T, Phizicky EM. De Zoysa T, et al. Among authors: phizicky em. PLoS Genet. 2020 Aug 25;16(8):e1008893. doi: 10.1371/journal.pgen.1008893. eCollection 2020 Aug. PLoS Genet. 2020. PMID: 32841241 Free PMC article.

3

A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay.

De Zoysa T, Hauke AC, Iyer NR, Marcus E, Ostrowski SM, Fay JC, Phizicky EM. De Zoysa T, et al. Among authors: phizicky em. bioRxiv [Preprint]. 2023 Sep 18:2023.09.18.558340. doi: 10.1101/2023.09.18.558340. bioRxiv. 2023. Update in: PLoS Genet. 2024 Jan 31;20(1):e1011146. doi: 10.1371/journal.pgen.1011146 PMID: 37790432 Free PMC article. Updated. Preprint.

4

S. cerevisiae Trm140 has two recognition modes for 3-methylcytidine modification of the anticodon loop of tRNA substrates.

Han L, Marcus E, D'Silva S, Phizicky EM. Han L, et al. Among authors: phizicky em. RNA. 2017 Mar;23(3):406-419. doi: 10.1261/rna.059667.116. Epub 2016 Dec 21. RNA. 2017. PMID: 28003514 Free PMC article.

5

Mutations in the anticodon stem of tRNA cause accumulation and Met22-dependent decay of pre-tRNA in yeast.

Payea MJ, Hauke AC, De Zoysa T, Phizicky EM. Payea MJ, et al. Among authors: phizicky em. RNA. 2020 Jan;26(1):29-43. doi: 10.1261/rna.073155.119. Epub 2019 Oct 16. RNA. 2020. PMID: 31619505 Free PMC article.

6

A semi-quantitative pull-down assay to study tRNA substrate specificity of modification enzymes.

Han L, Marcus E, Phizicky EM. Han L, et al. Among authors: phizicky em. Methods Enzymol. 2021;658:359-377. doi: 10.1016/bs.mie.2021.06.010. Epub 2021 Jul 14. Methods Enzymol. 2021. PMID: 34517954

7

Widespread temperature sensitivity and tRNA decay due to mutations in a yeast tRNA.

Payea MJ, Sloma MF, Kon Y, Young DL, Guy MP, Zhang X, De Zoysa T, Fields S, Mathews DH, Phizicky EM. Payea MJ, et al. Among authors: phizicky em. RNA. 2018 Mar;24(3):410-422. doi: 10.1261/rna.064642.117. Epub 2017 Dec 19. RNA. 2018. PMID: 29259051 Free PMC article.

8

Conditional accumulation of toxic tRNAs to cause amino acid misincorporation.

Zimmerman SM, Kon Y, Hauke AC, Ruiz BY, Fields S, Phizicky EM. Zimmerman SM, et al. Among authors: phizicky em. Nucleic Acids Res. 2018 Sep 6;46(15):7831-7843. doi: 10.1093/nar/gky623. Nucleic Acids Res. 2018. PMID: 30007351 Free PMC article.

9

High-Throughput Small RNA Sequencing Enhanced by AlkB-Facilitated RNA de-Methylation (ARM-Seq).

Hrabeta-Robinson E, Marcus E, Cozen AE, Phizicky EM, Lowe TM. Hrabeta-Robinson E, et al. Among authors: phizicky em. Methods Mol Biol. 2017;1562:231-243. doi: 10.1007/978-1-4939-6807-7_15. Methods Mol Biol. 2017. PMID: 28349464 Free PMC article.

10

Initiator tRNA lacking 1-methyladenosine is targeted by the rapid tRNA decay pathway in evolutionarily distant yeast species.

Tasak M, Phizicky EM. Tasak M, et al. Among authors: phizicky em. PLoS Genet. 2022 Jul 28;18(7):e1010215. doi: 10.1371/journal.pgen.1010215. eCollection 2022 Jul. PLoS Genet. 2022. PMID: 35901126 Free PMC article.

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