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TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue.
Zhao G, Xue L, Weiner AI, Gong N, Adams-Tzivelekidis S, Wong J, Gentile ME, Nottingham AN, Basil MC, Lin SM, Niethamer TK, Diamond JM, Bermudez CA, Cantu E, Han X, Cao Y, Alameh MG, Weissman D, Morrisey EE, Mitchell MJ, Vaughan AE. Zhao G, et al. Among authors: mitchell mj. Sci Transl Med. 2024 Jan 31;16(732):eadg6229. doi: 10.1126/scitranslmed.adg6229. Epub 2024 Jan 31. Sci Transl Med. 2024. PMID: 38295183
Nanomaterials for T-cell cancer immunotherapy.
Gong N, Sheppard NC, Billingsley MM, June CH, Mitchell MJ. Gong N, et al. Among authors: mitchell mj. Nat Nanotechnol. 2021 Jan;16(1):25-36. doi: 10.1038/s41565-020-00822-y. Epub 2021 Jan 12. Nat Nanotechnol. 2021. PMID: 33437036 Review.
Ionizable lipid nanoparticles for in utero mRNA delivery.
Riley RS, Kashyap MV, Billingsley MM, White B, Alameh MG, Bose SK, Zoltick PW, Li H, Zhang R, Cheng AY, Weissman D, Peranteau WH, Mitchell MJ. Riley RS, et al. Among authors: mitchell mj. Sci Adv. 2021 Jan 13;7(3):eaba1028. doi: 10.1126/sciadv.aba1028. Print 2021 Jan. Sci Adv. 2021. PMID: 33523869 Free PMC article.
Amniotic fluid stabilized lipid nanoparticles for in utero intra-amniotic mRNA delivery.
Swingle KL, Billingsley MM, Bose SK, White B, Palanki R, Dave A, Patel SK, Gong N, Hamilton AG, Alameh MG, Weissman D, Peranteau WH, Mitchell MJ. Swingle KL, et al. Among authors: mitchell mj. J Control Release. 2022 Jan;341:616-633. doi: 10.1016/j.jconrel.2021.10.031. Epub 2021 Nov 3. J Control Release. 2022. PMID: 34742747 Free PMC article.
An ionizable lipid toolbox for RNA delivery.
Han X, Zhang H, Butowska K, Swingle KL, Alameh MG, Weissman D, Mitchell MJ. Han X, et al. Among authors: mitchell mj. Nat Commun. 2021 Dec 13;12(1):7233. doi: 10.1038/s41467-021-27493-0. Nat Commun. 2021. PMID: 34903741 Free PMC article.
Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE).
Parhiz H, Brenner JS, Patel PN, Papp TE, Shahnawaz H, Li Q, Shi R, Zamora ME, Yadegari A, Marcos-Contreras OA, Natesan A, Pardi N, Shuvaev VV, Kiseleva R, Myerson JW, Uhler T, Riley RS, Han X, Mitchell MJ, Lam K, Heyes J, Weissman D, Muzykantov VR. Parhiz H, et al. Among authors: mitchell mj. J Control Release. 2022 Apr;344:50-61. doi: 10.1016/j.jconrel.2021.12.027. Epub 2021 Dec 23. J Control Release. 2022. PMID: 34953981 Free PMC article.
Rational design of anti-inflammatory lipid nanoparticles for mRNA delivery.
Zhang H, Han X, Alameh MG, Shepherd SJ, Padilla MS, Xue L, Butowska K, Weissman D, Mitchell MJ. Zhang H, et al. Among authors: mitchell mj. J Biomed Mater Res A. 2022 May;110(5):1101-1108. doi: 10.1002/jbm.a.37356. Epub 2022 Jan 25. J Biomed Mater Res A. 2022. PMID: 35076171 Free PMC article.
377 results