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Durvalumab with or without bevacizumab with transarterial chemoembolisation in hepatocellular carcinoma (EMERALD-1): a multiregional, randomised, double-blind, placebo-controlled, phase 3 study.
Sangro B, Kudo M, Erinjeri JP, Qin S, Ren Z, Chan SL, Arai Y, Heo J, Mai A, Escobar J, Lopez Chuken YA, Yoon JH, Tak WY, Breder VV, Suttichaimongkol T, Bouattour M, Lin SM, Peron JM, Nguyen QT, Yan L, Chiu CF, Santos FA, Veluvolu A, Thungappa SC, Matos M, Żotkiewicz M, Udoye SI, Kurland JF, Cohen GJ, Lencioni R; EMERALD-1 Investigators. Sangro B, et al. Lancet. 2025 Jan 8:S0140-6736(24)02551-0. doi: 10.1016/S0140-6736(24)02551-0. Online ahead of print. Lancet. 2025. PMID: 39798579
A high-throughput search for intracellular factors that affect RNA folding identifies E. coli proteins PepA and YagL as RNA chaperones that promote RNA remodelling.
Rojano-Nisimura AM, Miller LG, Anantharaman A, Middleton AT, Kibret E, Jung SH, Russell R, Contreras LM. Rojano-Nisimura AM, et al. Among authors: contreras lm. RNA Biol. 2024 Jan;21(1):13-30. doi: 10.1080/15476286.2024.2429956. Epub 2024 Nov 22. RNA Biol. 2024. PMID: 39576267 Free PMC article.
Selective 8-oxo-rG stalling occurs in the catalytic core of polynucleotide phosphorylase (PNPase) during degradation.
Miller LG, Kim W, Schowe S, Taylor K, Han R, Jain V, Park R, Sherman M, Fang J, Ramirez H, Ellington A, Tamamis P, Resendiz MJE, Zhang YJ, Contreras L. Miller LG, et al. Among authors: contreras l. Proc Natl Acad Sci U S A. 2024 Nov 12;121(46):e2317865121. doi: 10.1073/pnas.2317865121. Epub 2024 Nov 4. Proc Natl Acad Sci U S A. 2024. PMID: 39495922 Free PMC article.
Stricturing Crohn's disease and intestinal endometriosis: An unusual coexistence.
Carvajal F, López F, Núñez P, Contreras L, Quera R. Carvajal F, et al. Among authors: contreras l. Rev Gastroenterol Mex (Engl Ed). 2024 Oct-Dec;89(4):550-553. doi: 10.1016/j.rgmxen.2024.10.007. Epub 2024 Oct 11. Rev Gastroenterol Mex (Engl Ed). 2024. PMID: 39393974 Free article. No abstract available.
405 results