Rabies virus-based barcoded neuroanatomy resolved by single-cell RNA and in situ sequencing.
Zhang A, Jin L, Yao S, Matsuyama M, van Velthoven CTJ, Sullivan HA, Sun N, Kellis M, Tasic B, Wickersham I, Chen X.
Zhang A, et al.
Elife. 2024 Feb 6;12:RP87866. doi: 10.7554/eLife.87866.
Elife. 2024.
PMID: 38319699
Free PMC article.
This pathogen travels exclusively from 'postsynaptic' to 'presynaptic' neurons - from the cell that receives a message at a synapse, back to the one that sends it. A modified variant of the rabies virus can therefore be used to reveal the presynaptic cells co …
This pathogen travels exclusively from 'postsynaptic' to 'presynaptic' neurons - from the cell that receives a message at a sy …