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E3 ubiquitin ligase Herc3 deficiency leads to accumulation of subretinal microglia and retinal neurodegeneration.
Zegeye Y, Aredo B, Yuksel S, Kirman DC, Kumar A, Chen B, Turpin E, Shresta S, He YG, Gautron L, Tang M, Li X, DiCesare SM, Hulleman JD, Xing C, Ludwig S, Moresco EMY, Beutler BA, Ufret-Vincenty RL. Zegeye Y, et al. Among authors: gautron l. Sci Rep. 2024 Feb 6;14(1):3010. doi: 10.1038/s41598-024-53731-8. Sci Rep. 2024. PMID: 38321224 Free PMC article.
Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice.
Zhang Z, Shao M, Hepler C, Zi Z, Zhao S, An YA, Zhu Y, Ghaben AL, Wang MY, Li N, Onodera T, Joffin N, Crewe C, Zhu Q, Vishvanath L, Kumar A, Xing C, Wang QA, Gautron L, Deng Y, Gordillo R, Kruglikov I, Kusminski CM, Gupta RK, Scherer PE. Zhang Z, et al. Among authors: gautron l. J Clin Invest. 2019 Dec 2;129(12):5327-5342. doi: 10.1172/JCI130239. J Clin Invest. 2019. PMID: 31503545 Free PMC article.
Forward genetic analysis using OCT screening identifies Sfxn3 mutations leading to progressive outer retinal degeneration in mice.
Chen B, Aredo B, Ding Y, Zhong X, Zhu Y, Zhao CX, Kumar A, Xing C, Gautron L, Lyon S, Russell J, Li X, Tang M, Anderton P, Ludwig S, Moresco EMY, Beutler B, Ufret-Vincenty RL. Chen B, et al. Among authors: gautron l. Proc Natl Acad Sci U S A. 2020 Jun 9;117(23):12931-12942. doi: 10.1073/pnas.1921224117. Epub 2020 May 26. Proc Natl Acad Sci U S A. 2020. PMID: 32457148 Free PMC article.
Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.
Wang Y, Cao L, Lee CY, Matsuo T, Wu K, Asher G, Tang L, Saitoh T, Russell J, Klewe-Nebenius D, Wang L, Soya S, Hasegawa E, Chérasse Y, Zhou J, Li Y, Wang T, Zhan X, Miyoshi C, Irukayama Y, Cao J, Meeks JP, Gautron L, Wang Z, Sakurai K, Funato H, Sakurai T, Yanagisawa M, Nagase H, Kobayakawa R, Kobayakawa K, Beutler B, Liu Q. Wang Y, et al. Among authors: gautron l. Nat Commun. 2018 May 23;9(1):2041. doi: 10.1038/s41467-018-04324-3. Nat Commun. 2018. PMID: 29795268 Free PMC article.
82 results