A cell-adapted SARS-CoV-2 mutant, showing a deletion in the spike protein spanning the furin cleavage site, has reduced virulence at the lung level in K18-hACE2 mice.
Valleriani F, Di Pancrazio C, Spedicato M, Di Teodoro G, Malatesta D, Petrova T, Profeta F, Colaianni ML, Berjaoui S, Puglia I, Caporale M, Rossi E, Marcacci M, Luciani M, Sacchini F, Portanti O, Bencivenga F, Decaro N, Bonfante F, Lorusso A.
Valleriani F, et al. Among authors: luciani m.
Virology. 2024 Apr;592:109997. doi: 10.1016/j.virol.2024.109997. Epub 2024 Jan 28.
Virology. 2024.
PMID: 38324940
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