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Page 1
BindCraft: one-shot design of functional protein binders.
Pacesa M, Nickel L, Schellhaas C, Schmidt J, Pyatova E, Kissling L, Barendse P, Choudhury J, Kapoor S, Alcaraz-Serna A, Cho Y, Ghamary KH, Vinué L, Yachnin BJ, Wollacott AM, Buckley S, Westphal AH, Lindhoud S, Georgeon S, Goverde CA, Hatzopoulos GN, Gönczy P, Muller YD, Schwank G, Swarts DC, Vecchio AJ, Schneider BL, Ovchinnikov S, Correia BE. Pacesa M, et al. bioRxiv [Preprint]. 2024 Dec 7:2024.09.30.615802. doi: 10.1101/2024.09.30.615802. bioRxiv. 2024. PMID: 39677777 Free PMC article. Preprint.
Computational design of soluble and functional membrane protein analogues.
Goverde CA, Pacesa M, Goldbach N, Dornfeld LJ, Balbi PEM, Georgeon S, Rosset S, Kapoor S, Choudhury J, Dauparas J, Schellhaas C, Kozlov S, Baker D, Ovchinnikov S, Vecchio AJ, Correia BE. Goverde CA, et al. Among authors: pacesa m. Nature. 2024 Jul;631(8020):449-458. doi: 10.1038/s41586-024-07601-y. Epub 2024 Jun 19. Nature. 2024. PMID: 38898281 Free PMC article.
Computational design of soluble functional analogues of integral membrane proteins.
Goverde CA, Pacesa M, Goldbach N, Dornfeld LJ, Balbi PEM, Georgeon S, Rosset S, Kapoor S, Choudhury J, Dauparas J, Schellhaas C, Kozlov S, Baker D, Ovchinnikov S, Vecchio AJ, Correia BE. Goverde CA, et al. Among authors: pacesa m. bioRxiv [Preprint]. 2024 Mar 7:2023.05.09.540044. doi: 10.1101/2023.05.09.540044. bioRxiv. 2024. Update in: Nature. 2024 Jul;631(8020):449-458. doi: 10.1038/s41586-024-07601-y PMID: 38496615 Free PMC article. Updated. Preprint.
An atlas of protein homo-oligomerization across domains of life.
Schweke H, Pacesa M, Levin T, Goverde CA, Kumar P, Duhoo Y, Dornfeld LJ, Dubreuil B, Georgeon S, Ovchinnikov S, Woolfson DN, Correia BE, Dey S, Levy ED. Schweke H, et al. Among authors: pacesa m. Cell. 2024 Feb 15;187(4):999-1010.e15. doi: 10.1016/j.cell.2024.01.022. Epub 2024 Feb 6. Cell. 2024. PMID: 38325366 Free article.
PAM-flexible genome editing with an engineered chimeric Cas9.
Zhao L, Koseki SRT, Silverstein RA, Amrani N, Peng C, Kramme C, Savic N, Pacesa M, Rodríguez TC, Stan T, Tysinger E, Hong L, Yudistyra V, Ponnapati MR, Jacobson JM, Church GM, Jakimo N, Truant R, Jinek M, Kleinstiver BP, Sontheimer EJ, Chatterjee P. Zhao L, et al. Among authors: pacesa m. Nat Commun. 2023 Oct 4;14(1):6175. doi: 10.1038/s41467-023-41829-y. Nat Commun. 2023. PMID: 37794046 Free PMC article.
De novo design of protein interactions with learned surface fingerprints.
Gainza P, Wehrle S, Van Hall-Beauvais A, Marchand A, Scheck A, Harteveld Z, Buckley S, Ni D, Tan S, Sverrisson F, Goverde C, Turelli P, Raclot C, Teslenko A, Pacesa M, Rosset S, Georgeon S, Marsden J, Petruzzella A, Liu K, Xu Z, Chai Y, Han P, Gao GF, Oricchio E, Fierz B, Trono D, Stahlberg H, Bronstein M, Correia BE. Gainza P, et al. Among authors: pacesa m. Nature. 2023 May;617(7959):176-184. doi: 10.1038/s41586-023-05993-x. Epub 2023 Apr 26. Nature. 2023. PMID: 37100904 Free PMC article.
PAM-Flexible Genome Editing with an Engineered Chimeric Cas9.
Koseki S, Hong L, Yudistyra V, Stan T, Tysinger E, Silverstein R, Kramme C, Amrani N, Savic N, Pacesa M, Rodriguez T, Ponnapati M, Jacobson J, Church G, Truant R, Jinek M, Kleinstiver B, Sontheimer E, Chatterjee P. Koseki S, et al. Among authors: pacesa m. Res Sq [Preprint]. 2023 Mar 7:rs.3.rs-2625838. doi: 10.21203/rs.3.rs-2625838/v1. Res Sq. 2023. Update in: Nat Commun. 2023 Oct 4;14(1):6175. doi: 10.1038/s41467-023-41829-y PMID: 36945419 Free PMC article. Updated. Preprint.
21 results