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Page 1
Structural basis of Δ9-THC analog activity at the Cannabinoid 1 receptor.
Gloriam D, Thorsen T, Kulkarni Y, Sykes D, Bøggild A, Drace T, Hompluem P, Iliopoulos-Tsoutsouvas C, Nikas S, Daver H, Makriyannis A, Nissen P, Gajhede M, Veprintsev D, Boesen T, Kastrup J. Gloriam D, et al. Among authors: iliopoulos tsoutsouvas c. Res Sq [Preprint]. 2024 May 21:rs.3.rs-4277209. doi: 10.21203/rs.3.rs-4277209/v1. Res Sq. 2024. PMID: 38826401 Free PMC article. Preprint.
Large library docking for cannabinoid-1 receptor agonists with reduced side effects.
Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, O'Brien ES, Stein RM, Craik V, Tran NK, Ganapathy S, Liu F, Shiimura Y, Tong F, Ho TC, Radchenko DS, Moroz YS, Rosado SR, Bhardwaj K, Benitez J, Liu Y, Kandasamy H, Normand C, Semache M, Sabbagh L, Glenn I, Irwin JJ, Kumar KK, Makriyannis A, Basbaum AI, Shoichet BK. Tummino TA, et al. Among authors: iliopoulos tsoutsouvas c. bioRxiv [Preprint]. 2024 Feb 28:2023.02.27.530254. doi: 10.1101/2023.02.27.530254. bioRxiv. 2024. PMID: 38328157 Free PMC article. Preprint.
Differential Enantiomer-Specific Signaling of Cannabidiol at CB1 Receptors.
Bosquez-Berger T, Wilson S, Iliopoulos-Tsoutsouvas C, Jiang S, Wager-Miller J, Nikas SP, Mackie KP, Makriyannis A, Straiker A. Bosquez-Berger T, et al. Among authors: iliopoulos tsoutsouvas c. Mol Pharmacol. 2022 Dec;102(6):259-268. doi: 10.1124/molpharm.121.000305. Epub 2022 Sep 24. Mol Pharmacol. 2022. PMID: 36153039 Free PMC article.
Altered sleep during spontaneous cannabinoid withdrawal in male mice.
Missig G, Mehta N, Robbins JO, Good CH, Iliopoulos-Tsoutsouvas C, Makriyannis A, Nikas SP, Bergman J, Carlezon WA Jr, Paronis CA. Missig G, et al. Among authors: iliopoulos tsoutsouvas c. Behav Pharmacol. 2022 Apr 1;33(2&3):195-205. doi: 10.1097/FBP.0000000000000674. Behav Pharmacol. 2022. PMID: 35288510 Free PMC article.
Evidence for spontaneous cannabinoid withdrawal in mice.
Paronis C, Iliopoulos-Tsoutsouvas C, Papanastasiou I, Makriyannis A, Bergman J, Nikas SP. Paronis C, et al. Among authors: iliopoulos tsoutsouvas c. Behav Pharmacol. 2022 Apr 1;33(2&3):184-194. doi: 10.1097/FBP.0000000000000665. Behav Pharmacol. 2022. PMID: 35288509 Free PMC article.
Improved cyclobutyl nabilone analogs as potent CB1 receptor agonists.
Papanastasiou IP, Georgiadis MO, Iliopoulos-Tsoutsouvas C, Paronis CA, Brust CA, Tran NK, Ji L, Ma X, Wood JT, Zvonok N, Tong F, Bohn LM, Nikas SP, Makriyannis A. Papanastasiou IP, et al. Among authors: iliopoulos tsoutsouvas c. Eur J Med Chem. 2022 Feb 15;230:114027. doi: 10.1016/j.ejmech.2021.114027. Epub 2021 Dec 27. Eur J Med Chem. 2022. PMID: 35051750
Synthon-based ligand discovery in virtual libraries of over 11 billion compounds.
Sadybekov AA, Sadybekov AV, Liu Y, Iliopoulos-Tsoutsouvas C, Huang XP, Pickett J, Houser B, Patel N, Tran NK, Tong F, Zvonok N, Jain MK, Savych O, Radchenko DS, Nikas SP, Petasis NA, Moroz YS, Roth BL, Makriyannis A, Katritch V. Sadybekov AA, et al. Among authors: iliopoulos tsoutsouvas c. Nature. 2022 Jan;601(7893):452-459. doi: 10.1038/s41586-021-04220-9. Epub 2021 Dec 15. Nature. 2022. PMID: 34912117 Free PMC article.
Novel Functionalized Cannabinoid Receptor Probes: Development of Exceptionally Potent Agonists.
Jiang S, Iliopoulos-Tsoutsouvas C, Tong F, Brust CA, Keenan CM, Raghav JG, Hua T, Wu S, Ho JH, Wu Y, Grim TW, Zvonok N, Thakur GA, Liu ZJ, Sharkey KA, Bohn LM, Nikas SP, Makriyannis A. Jiang S, et al. Among authors: iliopoulos tsoutsouvas c. J Med Chem. 2021 Apr 8;64(7):3870-3884. doi: 10.1021/acs.jmedchem.0c02053. Epub 2021 Mar 24. J Med Chem. 2021. PMID: 33761251
Synthesis of Functionalized Cannabilactones.
Liu Y, Ho TC, Baradwan M, Pascual Lopez-Alberca M, Iliopoulos-Tsoutsouvas C, Nikas SP, Makriyannis A. Liu Y, et al. Among authors: iliopoulos tsoutsouvas c. Molecules. 2020 Feb 6;25(3):684. doi: 10.3390/molecules25030684. Molecules. 2020. PMID: 32041131 Free PMC article.
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