Springer TA - Search Results

1

Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits.

Hao Y, Yan J, Fraser C, Jiang A, Anuganti M, Zhang R, Lloyd K, Jardine J, Coppola J, Meijers R, Li J, Springer TA. Hao Y, et al. Among authors: springer ta. bioRxiv [Preprint]. 2024 Jan 27:2024.01.26.577394. doi: 10.1101/2024.01.26.577394. bioRxiv. 2024. Update in: MAbs. 2024 Jan-Dec;16(1):2365891. doi: 10.1080/19420862.2024.2365891 PMID: 38328192 Free PMC article. Updated. Preprint.

2

Integrin extension enables ultrasensitive regulation by cytoskeletal force.

Li J, Springer TA. Li J, et al. Among authors: springer ta. Proc Natl Acad Sci U S A. 2017 May 2;114(18):4685-4690. doi: 10.1073/pnas.1704171114. Epub 2017 Apr 17. Proc Natl Acad Sci U S A. 2017. PMID: 28416675 Free PMC article.

3

Atypical interactions of integrin α_Vβ₈ with pro-TGF-β1.

Wang J, Dong X, Zhao B, Li J, Lu C, Springer TA. Wang J, et al. Among authors: springer ta. Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4168-E4174. doi: 10.1073/pnas.1705129114. Epub 2017 May 8. Proc Natl Acad Sci U S A. 2017. PMID: 28484027 Free PMC article.

4

Energy landscape differences among integrins establish the framework for understanding activation.

Li J, Springer TA. Li J, et al. Among authors: springer ta. J Cell Biol. 2018 Jan 2;217(1):397-412. doi: 10.1083/jcb.201701169. Epub 2017 Nov 9. J Cell Biol. 2018. PMID: 29122968 Free PMC article.

5

Low-affinity integrin states have faster ligand-binding kinetics than the high-affinity state.

Li J, Yan J, Springer TA. Li J, et al. Among authors: springer ta. Elife. 2021 Dec 2;10:e73359. doi: 10.7554/eLife.73359. Elife. 2021. PMID: 34854380 Free PMC article.

6

Regulation of integrin α5β1 conformational states and intrinsic affinities by metal ions and the ADMIDAS.

Anderson JM, Li J, Springer TA. Anderson JM, et al. Among authors: springer ta. Mol Biol Cell. 2022 May 15;33(6):ar56. doi: 10.1091/mbc.E21-11-0536. Epub 2022 Feb 2. Mol Biol Cell. 2022. PMID: 35108026 Free PMC article.

7

Loss of LRRC33-Dependent TGFβ1 Activation Enhances Antitumor Immunity and Checkpoint Blockade Therapy.

Jiang A, Qin Y, Springer TA. Jiang A, et al. Among authors: springer ta. Cancer Immunol Res. 2022 Apr 1;10(4):453-467. doi: 10.1158/2326-6066.CIR-21-0593. Cancer Immunol Res. 2022. PMID: 35181792 Free PMC article.

8

Dynamics of integrin α5β1, fibronectin, and their complex reveal sites of interaction and conformational change.

Su Y, Iacob RE, Li J, Engen JR, Springer TA. Su Y, et al. Among authors: springer ta. J Biol Chem. 2022 Sep;298(9):102323. doi: 10.1016/j.jbc.2022.102323. Epub 2022 Aug 2. J Biol Chem. 2022. PMID: 35931112 Free PMC article.

9

Single-molecule characterization of subtype-specific β1 integrin mechanics.

Jo MH, Li J, Jaumouillé V, Hao Y, Coppola J, Yan J, Waterman CM, Springer TA, Ha T. Jo MH, et al. Among authors: springer ta. Nat Commun. 2022 Dec 3;13(1):7471. doi: 10.1038/s41467-022-35173-w. Nat Commun. 2022. PMID: 36463259 Free PMC article.

10

Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits.

Hao Y, Yan J, Fraser C, Jiang A, Anuganti M, Zhang R, Lloyd K, Jardine J, Coppola J, Meijers R, Li J, Springer TA. Hao Y, et al. Among authors: springer ta. MAbs. 2024 Jan-Dec;16(1):2365891. doi: 10.1080/19420862.2024.2365891. Epub 2024 Jun 18. MAbs. 2024. PMID: 38889315 Free PMC article.

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