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Relative deficiency in interferon-γ-secreting CD4+ T cells is strongly associated with poorer COVID-19 vaccination responses in older adults.
Ho VWT, Boon LH, Cui J, Juequn Z, Shunmuganathan B, Gupta R, Tan NYJ, Qian X, Purushotorman K; SCOPE Cohort Study Group; Fong SW, Renia L, Ng LFP, Angeli V, Chen J, Kennedy BK, Ong CWM, Macary PA. Ho VWT, et al. Aging Cell. 2024 Apr;23(4):e14099. doi: 10.1111/acel.14099. Epub 2024 Feb 5. Aging Cell. 2024. PMID: 38317404 Free PMC article.
Author Correction: Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta wave.
Goh YS, Fong SW, Tay MZ, Rouers A, Chang ZW, Chavatte JM, Hor PX, Loh CY, Huang Y, Tan YJ, Wang B, Ngoh EZX, Mohd Salleh SN, Lee RTC, Lim G; NCID Study Group; COVID-Study Group; Maurer-Stroh S, Wang CI, Leo YS, Lin RTP, Lam MC, Lye DC, Young BE, Ng LFP, Renia L. Goh YS, et al. Sci Rep. 2024 Jan 17;14(1):1492. doi: 10.1038/s41598-024-51484-y. Sci Rep. 2024. PMID: 38233454 Free PMC article. No abstract available.
Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2.
Gu Y, Shunmuganathan B, Qian X, Gupta R, Tan RSW, Kozma M, Purushotorman K, Murali TM, Tan NYJ, Preiser PR, Lescar J, Nasir H, Somani J, Tambyah PA; SCOPE Cohort Study Group; Smith KGC, Renia L, Ng LFP, Lye DC, Young BE, MacAry PA. Gu Y, et al. Sci Rep. 2023 Dec 9;13(1):21810. doi: 10.1038/s41598-023-49231-w. Sci Rep. 2023. PMID: 38071323 Free PMC article.
Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta wave.
Goh YS, Fong SW, Tay MZ, Rouers A, Chang ZW, Chavatte JM, Hor PX, Loh CY, Huang Y, Tan YJ, Wang B, Ngoh EZX, Mohd Salleh SN, Lee RTC, Lim G; NCID Study Group; COVID-Study Group; Maurer-Stroh S, Wang CI, Leo YS, Lin RTP, Lam MC, Lye DC, Young BE, Ng LFP, Renia L. Goh YS, et al. Sci Rep. 2023 Nov 7;13(1):19331. doi: 10.1038/s41598-023-46800-x. Sci Rep. 2023. PMID: 37935965 Free PMC article.
Prolonged inflammation in patients hospitalized for coronavirus disease 2019 (COVID-19) resolves 2 years after infection.
Fong SW, Goh YS, Torres-Ruesta A, Chang ZW, Chan YH, Neo VK, Lee B, Duan K, Amrun SN, Yeo NK, Chen HV, Tay MZ, Carissimo G; COVID-19 Study Group; NCID Study Group; Tan SY, Leo YS, Lye DC, Renia L, Young BE, Ng LFP. Fong SW, et al. Among authors: amrun sn. J Med Virol. 2023 May;95(5):e28774. doi: 10.1002/jmv.28774. J Med Virol. 2023. PMID: 37212320
Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections.
Goh YS, Fong SW, Hor PX, Amrun SN, Lee CY, Young BE, Chia PY, Tambyah PA, Kalimuddin S, Pada S, Tan SY, Sun LJ, Chen MI, Leo YS, Lye DC, Ng LFP, Renia L. Goh YS, et al. Among authors: amrun sn. Front Microbiol. 2022 Nov 22;13:1043049. doi: 10.3389/fmicb.2022.1043049. eCollection 2022. Front Microbiol. 2022. PMID: 36483199 Free PMC article.
Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals.
Goh YS, Rouers A, Fong SW, Zhuo NZ, Hor PX, Loh CY, Huang Y, Neo VK, Kam IKJ, Wang B, Ngoh EZX, Salleh SNM, Lee RTC, Pada S, Sun LJ, Ong DLS, Somani J, Lee ES; NCID Study Group; COVID-19 Study Group; Maurer-Stroh S, Wang CI, Leo YS, Ren EC, Lye DC, Young BE, Ng LFP, Renia L. Goh YS, et al. Front Immunol. 2022 Nov 14;13:1031852. doi: 10.3389/fimmu.2022.1031852. eCollection 2022. Front Immunol. 2022. PMID: 36451833 Free PMC article.
Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose.
Renia L, Goh YS, Rouers A, Le Bert N, Chia WN, Chavatte JM, Fong SW, Chang ZW, Zhuo NZ, Tay MZ, Chan YH, Tan CW, Yeo NK, Amrun SN, Huang Y, Wong JXE, Hor PX, Loh CY, Wang B, Ngoh EZX, Salleh SNM, Carissimo G, Dowla S, Lim AJ, Zhang J, Lim JME, Wang CI, Ding Y, Pada S, Sun LJ, Somani J, Lee ES, Ong DLS; SCOPE Cohort Study Group; Leo YS, MacAry PA, Lin RTP, Wang LF, Ren EC, Lye DC, Bertoletti A, Young BE, Ng LFP. Renia L, et al. Among authors: amrun sn. Nat Commun. 2022 Aug 8;13(1):4615. doi: 10.1038/s41467-022-32312-1. Nat Commun. 2022. PMID: 35941158 Free PMC article.
Discrepant serological findings in SARS-CoV-2 PCR-negative hospitalized patients with fever and acute respiratory symptoms during the pandemic.
Cross GB, Naftalin CM, Ngiam JN, Bagdasarian N, Poh CM, Goh YS, Chia WN, Amrun SN, Tham SM, Teng H, Alagha R, Kumar SK, Tan SSY, Wang LF, Tambyah PA, Renia L, Fisher D, Ng LFP. Cross GB, et al. Among authors: amrun sn. J Med Virol. 2022 Jun;94(6):2460-2470. doi: 10.1002/jmv.27656. Epub 2022 Mar 12. J Med Virol. 2022. PMID: 35171507 Free PMC article.
44 results