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Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead.
Dayan Elshan NGR, Wolff KC, Riva L, Woods AK, Grabovyi G, Wilson K, Pedroarena J, Ghorai S, Nazarian A, Weiss F, Liu Y, Mazumdar W, Song L, Okwor N, Malvin J, Bakowski MA, Beutler N, Kirkpatrick MG, Gebara-Lamb A, Huang E, Nguyen-Tran VTB, Chi V, Li S, Rogers TF, McNamara CW, Gupta AK, Rahimi A, Chen JJ, Joseph SB, Schultz PG, Chatterjee AK. Dayan Elshan NGR, et al. Among authors: wilson k. J Med Chem. 2024 Feb 22;67(4):2369-2378. doi: 10.1021/acs.jmedchem.3c01938. Epub 2024 Feb 9. J Med Chem. 2024. PMID: 38335279 Free PMC article.
Correction to "Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead".
Elshan NGRD, Wolff KC, Riva L, Woods AK, Grabovyi G, Wilson K, Pedroarena J, Ghorai S, Nazarian A, Weiss F, Liu Y, Mazumdar W, Song L, Okwor N, Malvin J, Liu D, Bakowski MA, Beutler N, Kirkpatrick MG, Gebara-Lamb A, Huang E, Nguyen-Tran VTB, Chi V, Li S, Rogers TF, McNamara CW, Gupta AK, Rahimi A, Chen JJ, Joseph SB, Schultz PG, Chatterjee AK. Elshan NGRD, et al. Among authors: wilson k. J Med Chem. 2024 Jun 27;67(12):10508-10509. doi: 10.1021/acs.jmedchem.4c01269. Epub 2024 Jun 14. J Med Chem. 2024. PMID: 38875353 Free PMC article. No abstract available.
A non-randomised open-label exploratory 'window of opportunity' study of TG02 treatment in patients with locally advanced primary and recurrent RAS mutant colorectal cancer.
Roth S, Wilson KC, Ramsay RG, Mitchell C, Sampurno S, Pham TD, Huei Kong JC, Wong SQ, Heriot AG, Deva S, Burge M, Sverdrup C, Moller AS, Kuryk L, Eriksen JA, Jaderberg M, Zalcberg JR, Michael M. Roth S, et al. Among authors: wilson kc. Heliyon. 2024 Dec 19;11(1):e41364. doi: 10.1016/j.heliyon.2024.e41364. eCollection 2025 Jan 15. Heliyon. 2024. PMID: 39811281 Free PMC article.
Pathobiont-triggered induction of epithelial IDO1 drives regional susceptibility to Inflammatory Bowel Disease.
Spencer PN, Wang J, Smith EP, Spiga L, Simmons AJ, Kim T, Kim W, Brown ME, Yang Y, Kaur H, Xu Y, Kang SW, Helou MD, Lee MA, Zheng L, Arceneaux D, Tasneem N, Mueller KD, Kuddar OS, Harned MH, Ro J, Li J, Banerjee A, Markham NO, Wilson KT, Coburn LA, Goettel JA, Liu Q, Washington MK, Valdivia RH, Zhu W, Lau KS. Spencer PN, et al. Among authors: wilson kt. bioRxiv [Preprint]. 2025 Jan 4:2025.01.04.630951. doi: 10.1101/2025.01.04.630951. bioRxiv. 2025. PMID: 39803424 Free PMC article. Preprint.
Discovery of FHD-286, a First-in-Class, Orally Bioavailable, Allosteric Dual Inhibitor of the Brahma Homologue (BRM) and Brahma-Related Gene 1 (BRG1) ATPase Activity for the Treatment of SWItch/Sucrose Non-Fermentable (SWI/SNF) Dependent Cancers.
Vaswani RG, Huang DS, Anthony N, Xu L, Centore R, Schiller S, Li Z, Fan H, Setser J, Zawadzke LE, Davenport Y, Chen X, Barnash K, Adam A, Ichikawa K, Huang L, Gu CH, Voigt J, Millan D, Chan HM, Decicco C, Hentemann M, Bellon SF, Wilson KJ. Vaswani RG, et al. Among authors: wilson kj. J Med Chem. 2025 Jan 12. doi: 10.1021/acs.jmedchem.4c02535. Online ahead of print. J Med Chem. 2025. PMID: 39801091
Low Prevalence of SARS-CoV-2 in Farmed and Free-Ranging White-Tailed Deer in Florida.
Grace SG, Wilson KN, Dorleans R, White ZS, Pu R, Gaudreault NN, Cool K, Campos Krauer JM, Franklin LE, Clemons BC, Subramaniam K, Richt JA, Lednicky JA, Long MT, Wisely SM. Grace SG, et al. Among authors: wilson kn. Viruses. 2024 Dec 6;16(12):1886. doi: 10.3390/v16121886. Viruses. 2024. PMID: 39772194 Free PMC article.
5,898 results