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Genome-wide association analyses using machine learning-based phenotyping reveal genetic architecture of occupational creativity and overlap with psychiatric disorders.
Kim H, Ahn Y, Yoon J, Jung K, Kim S, Shim I, Park TH, Ko H, Jung SH, Kim J, Park S, Lee DJ, Choi S, Cha S, Kim B, Cho MY, Cho H, Kim DS, Jang Y, Ihm HK, Park WY, Bakhshi H, O Connell KS, Andreassen OA, Kendler KS, Myung W, Won HH. Kim H, et al. Among authors: kendler ks. Psychiatry Res. 2024 Mar;333:115753. doi: 10.1016/j.psychres.2024.115753. Epub 2024 Feb 1. Psychiatry Res. 2024. PMID: 38335777
Genomewide association studies: history, rationale, and prospects for psychiatric disorders.
Psychiatric GWAS Consortium Coordinating Committee; Cichon S, Craddock N, Daly M, Faraone SV, Gejman PV, Kelsoe J, Lehner T, Levinson DF, Moran A, Sklar P, Sullivan PF. Psychiatric GWAS Consortium Coordinating Committee, et al. Am J Psychiatry. 2009 May;166(5):540-56. doi: 10.1176/appi.ajp.2008.08091354. Epub 2009 Apr 1. Am J Psychiatry. 2009. PMID: 19339359 Free PMC article. Review.
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.
Hsu YH, Pintacuda G, Liu R, Nacu E, Kim A, Tsafou K, Petrossian N, Crotty W, Suh JM, Riseman J, Martin JM, Biagini JC, Mena D, Ching JKT, Malolepsza E, Li T, Singh T, Ge T, Egri SB, Tanenbaum B, Stanclift CR, Apffel AM; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Stanley Global Asia Initiatives; Carr SA, Schenone M, Jaffe J, Fornelos N, Huang H, Eggan KC, Lage K. Hsu YH, et al. iScience. 2023 Apr 18;26(5):106701. doi: 10.1016/j.isci.2023.106701. eCollection 2023 May 19. iScience. 2023. PMID: 37207277 Free PMC article.
Distinct genetic liability profiles define clinically relevant patient strata across common diseases.
Trastulla L, Dolgalev G, Moser S, Jiménez-Barrón LT, Andlauer TFM, von Scheidt M; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Budde M, Heilbronner U, Papiol S, Teumer A, Homuth G, Völzke H, Dörr M, Falkai P, Schulze TG, Gagneur J, Iorio F, Müller-Myhsok B, Schunkert H, Ziller MJ. Trastulla L, et al. Nat Commun. 2024 Jul 1;15(1):5534. doi: 10.1038/s41467-024-49338-2. Nat Commun. 2024. PMID: 38951512 Free PMC article.
Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions.
Maury EA, Sherman MA, Genovese G, Gilgenast TG, Kamath T, Burris SJ, Rajarajan P, Flaherty E, Akbarian S, Chess A, McCarroll SA, Loh PR, Phillips-Cremins JE, Brennand KJ, Macosko EZ, Walters JTR, O'Donovan M, Sullivan P; Psychiatric Genomic Consortium Schizophrenia and CNV workgroup; Brain Somatic Mosaicism Network; Sebat J, Lee EA, Walsh CA. Maury EA, et al. Cell Genom. 2023 Jul 6;3(8):100356. doi: 10.1016/j.xgen.2023.100356. eCollection 2023 Aug 9. Cell Genom. 2023. PMID: 37601975 Free PMC article.
Polygenic analyses show important differences between MDD symptoms collected using PHQ9 and CIDI-SF.
Huang L, Tang S, Rietkerk J, Appadurai V, Krebs MD, Schork AJ, Werge T, Zuber V, Kendler K, Cai N. Huang L, et al. medRxiv [Preprint]. 2023 Mar 1:2023.02.27.23286527. doi: 10.1101/2023.02.27.23286527. medRxiv. 2023. Update in: Biol Psychiatry. 2024 Jun 15;95(12):1110-1121. doi: 10.1016/j.biopsych.2023.11.021 PMID: 36909638 Free PMC article. Updated. Preprint.
Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research.
Cai N, Verhulst B, Andreassen OA, Buitelaar J, Edenberg HJ, Hettema JM, Gandal M, Grotzinger A, Jonas K, Lee P, Mallard TT, Mattheisen M, Neale MC, Nurnberger JI Jr, Peyrout W, Tucker-Drob EM, Smoller JW, Kendler KS. Cai N, et al. Among authors: kendler ks. Mol Psychiatry. 2024 Dec 27. doi: 10.1038/s41380-024-02878-x. Online ahead of print. Mol Psychiatry. 2024. PMID: 39730880 Review.
1,416 results