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Page 1
Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein.
Dacon C, Moskovitz R, Swearingen K, Da Silva Pereira L, Flores-Garcia Y, Aleshnick M, Kanatani S, Flynn B, Molina-Cruz A, Wollenberg K, Traver M, Kirtley P, Purser L, Dillon M, Bonilla B, Franco A, Petros S, Kritzberg J, Tucker C, Paez GG, Gupta P, Shears MJ, Pazzi J, Edgar JM, Teng AA, Belmonte A, Oda K, Doumbo S, Krymskaya L, Skinner J, Li S, Ghosal S, Kayentao K, Ongoiba A, Vaughan A, Campo JJ, Traore B, Barillas-Mury C, Wijayalath W, Idris A, Crompton PD, Sinnis P, Wilder BK, Zavala F, Seder RA, Wilson IA, Tan J. Dacon C, et al. Among authors: flores garcia y. Science. 2025 Jan 3;387(6729):eadr0510. doi: 10.1126/science.adr0510. Epub 2025 Jan 3. Science. 2025. PMID: 39745947
ProC6C, a novel multi-stage malaria vaccine, elicits functional antibodies against the minor and central repeats of the Circumsporozoite Protein in human adults.
Plieskatt J, Ofori EA, Naghizadeh M, Miura K, Flores-Garcia Y, Borbye-Lorenzen N, Tiono AB, Skogstrand K, Sagara I, Zavala F, Theisen M. Plieskatt J, et al. Among authors: flores garcia y. Front Immunol. 2024 Nov 1;15:1481829. doi: 10.3389/fimmu.2024.1481829. eCollection 2024. Front Immunol. 2024. PMID: 39555079 Free PMC article. Clinical Trial.
Mosquito salivary apyrase regulates blood meal hemostasis and facilitates malaria parasite transmission.
Pala ZR, Alves E Silva TL, Minai M, Crews B, Patino-Martinez E, Carmona-Rivera C, Valenzuela Leon PC, Martin-Martin I, Flores-Garcia Y, Cachau RE, Muslinkina L, Gittis AG, Srivastava N, Garboczi DN, Alves DA, Kaplan MJ, Fischer E, Calvo E, Vega-Rodriguez J. Pala ZR, et al. Among authors: flores garcia y. Nat Commun. 2024 Sep 18;15(1):8194. doi: 10.1038/s41467-024-52502-3. Nat Commun. 2024. PMID: 39294191 Free PMC article.
Immature dendritic cell-targeting mRNA vaccine expressing PfCSP enhances protective immune responses against Plasmodium liver infection.
Yanik S, Venkatesh V, Gordy JT, Gabriel-Alameh M, Meza J, Li Y, Glass E, Flores-Garcia Y, Tam Y, Chaiyawong N, Sarkar D, Weissman D, Markham R, Srinivasan P. Yanik S, et al. Among authors: flores garcia y. Res Sq [Preprint]. 2024 Jul 9:rs.3.rs-4656309. doi: 10.21203/rs.3.rs-4656309/v1. Res Sq. 2024. PMID: 39041038 Free PMC article. Preprint.
Vaccines and monoclonal antibodies: new tools for malaria control.
Miura K, Flores-Garcia Y, Long CA, Zavala F. Miura K, et al. Among authors: flores garcia y. Clin Microbiol Rev. 2024 Jun 13;37(2):e0007123. doi: 10.1128/cmr.00071-23. Epub 2024 Apr 24. Clin Microbiol Rev. 2024. PMID: 38656211 Review.
A candidate antibody drug for prevention of malaria.
Williams KL, Guerrero S, Flores-Garcia Y, Kim D, Williamson KS, Siska C, Smidt P, Jepson SZ, Li K, Dennison SM, Mathis-Torres S, Chen X, Wille-Reece U, MacGill RS, Walker M, Jongert E, King CR, Ockenhouse C, Glanville J, Moon JE, Regules JA, Tan YC, Cavet G, Lippow SM, Robinson WH, Dutta S, Tomaras GD, Zavala F, Ketchem RR, Emerling DE. Williams KL, et al. Among authors: flores garcia y. Nat Med. 2024 Jan;30(1):117-129. doi: 10.1038/s41591-023-02659-z. Epub 2024 Jan 2. Nat Med. 2024. PMID: 38167935 Free PMC article.
Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Thai E, Murugan R, Binter Š, Burn Aschner C, Prieto K, Kassardjian A, Obraztsova AS, Kang RW, Flores-Garcia Y, Mathis-Torres S, Li K, Horn GQ, Huntwork RHC, Bolscher JM, de Bruijni MHC, Sauerwein R, Dennison SM, Tomaras GD, Zavala F, Kellam P, Wardemann H, Julien JP. Thai E, et al. Among authors: flores garcia y. Cell Rep. 2023 Nov 28;42(11):113330. doi: 10.1016/j.celrep.2023.113330. Epub 2023 Oct 28. Cell Rep. 2023. PMID: 38007690 Free PMC article.
44 results