Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

3,848 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Nuclear transport protein suppresses Tau neurodegeneration.
Chinnathambi S, Adithyan A, Suresh S, Velmurugan G, Chandrashekar M, Sahu S, Mishra M. Chinnathambi S, et al. Adv Protein Chem Struct Biol. 2025;143:363-385. doi: 10.1016/bs.apcsb.2024.07.001. Epub 2024 Jul 26. Adv Protein Chem Struct Biol. 2025. PMID: 39843141 Review.
The decrease in lamin B and increasing levels of lamin A along with C in AD-affected brain areas highlight the disease's intricacy. Furthermore, Tau internalization in the nucleus and interaction with nuclear pore complexes worsen NPC dysfunction, which contributes …
The decrease in lamin B and increasing levels of lamin A along with C in AD-affected brain areas highlight the disease's intri …
Role of lamins in cellular physiology and cancer.
Chauhan R, Gupta A, Dagar G, Sharma S, Sadida HQ, Hashem S, Verghese AM, Tanwar M, Macha MA, Uddin S, Al-Shabeeb Akil AS, Pandita TK, Bhat AA, Singh M. Chauhan R, et al. Adv Protein Chem Struct Biol. 2025;143:119-153. doi: 10.1016/bs.apcsb.2024.06.002. Epub 2024 Jun 25. Adv Protein Chem Struct Biol. 2025. PMID: 39843134 Review.
Changes in lamin subtype composition within the nuclear lamina have significant implications for cancer development, impacting cellular stiffness, mobility, and the Epithelial-to-Mesenchymal Transition (EMT). Lamin A/C, in particular, plays multifaceted roles in can …
Changes in lamin subtype composition within the nuclear lamina have significant implications for cancer development, impacting cellular stif …
The role of the LINC complex in ageing and microgravity.
Lansweers I, van Rijthoven S, van Loon JJWA. Lansweers I, et al. Mech Ageing Dev. 2025 Jan 14;224:112028. doi: 10.1016/j.mad.2025.112028. Online ahead of print. Mech Ageing Dev. 2025. PMID: 39818253 Free article.
The nuclear lamin network passively responds to both active or passive cell movement through confinements.
Amiri S, Bos I, Reyssat E, Sykes C. Amiri S, et al. Soft Matter. 2025 Jan 13. doi: 10.1039/d4sm01137f. Online ahead of print. Soft Matter. 2025. PMID: 39801443
As a result, up to now, the interpretations on the lamin response mechanism are mainly speculative. Here, we quantitatively map the lamin A/C distribution in both a microfluidic migration device and a microfluidic aspiration device. ...
As a result, up to now, the interpretations on the lamin response mechanism are mainly speculative. Here, we quantitatively map the lamin …
FKBP10 Promotes the Muscle Invasion of Bladder Cancer via Lamin A Dysregulation.
Zhao X, Wang J, Tian S, Tang L, Cao S, Ye J, Cai T, Xuan Y, Zhang X, Li X, Li H. Zhao X, et al. Int J Biol Sci. 2025 Jan 1;21(2):758-771. doi: 10.7150/ijbs.105265. eCollection 2025. Int J Biol Sci. 2025. PMID: 39781460 Free PMC article.
Mechanistically, FKBP10 interacts with prelamin A and hinder the nuclear entry of prelamin A, thereby leading to the decrease in the nuclear lamin A, a key factor involved in nuclear atypia. In human BC tissues, nuclear lamin A is downregulated and neg …
Mechanistically, FKBP10 interacts with prelamin A and hinder the nuclear entry of prelamin A, thereby leading to the decrease in the nuclear …
Divergent Contribution of Cytoplasmic Actins to Nuclear Structure of Lung Cancer Cells.
Shagieva G, Dugina V, Burakov A, Levuschkina Y, Kudlay D, Boichuk S, Khromova N, Vasileva M, Kopnin P. Shagieva G, et al. Int J Mol Sci. 2024 Dec 19;25(24):13607. doi: 10.3390/ijms252413607. Int J Mol Sci. 2024. PMID: 39769373 Free PMC article.
In contrast, the suppression of gamma-actin led to upregulation of the lamin A/B ratio through an increase in A-type lamins. Histone H3 post-translational modifications display distinct patterns in response to decreased actin isoform expression. ...
In contrast, the suppression of gamma-actin led to upregulation of the lamin A/B ratio through an increase in A-type lamins. H …
Angiopoietin-2: A Therapeutic Target for Vascular Protection in Hutchinson-Gilford Progeria Syndrome.
Vakili S, Cao K. Vakili S, et al. Int J Mol Sci. 2024 Dec 18;25(24):13537. doi: 10.3390/ijms252413537. Int J Mol Sci. 2024. PMID: 39769300 Free PMC article. Review.
The abnormal accumulation of a toxic form of the lamin A protein known as progerin disrupts cellular functions, leading to various complications, including growth retardation, loss of subcutaneous fat, abnormal skin, alopecia, osteoporosis, and progressive joint con …
The abnormal accumulation of a toxic form of the lamin A protein known as progerin disrupts cellular functions, leading to var …
Imaging-Based Molecular Interaction Between Src and Lamin A/C Mechanosensitive Proteins in the Nucleus of Laminopathic Cells.
Petrini S, Bagnato G, Piccione M, D'Oria V, Apollonio V, Cappa M, Castiglioni C, Santorelli FM, Rizza T, Carrozzo R, Bertini ES, Peruzzi B. Petrini S, et al. Int J Mol Sci. 2024 Dec 13;25(24):13365. doi: 10.3390/ijms252413365. Int J Mol Sci. 2024. PMID: 39769130 Free PMC article.
Here, we demonstrated a tight relationship between lamin A/C and Src in skin fibroblasts from two laminopathic patients, assessed by advanced imaging-based microscopy techniques. ...All these results demonstrate a molecular interaction between Src and lamin …
Here, we demonstrated a tight relationship between lamin A/C and Src in skin fibroblasts from two laminopathic patients, asses …
3,848 results